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AB81468

Anti-Filaggrin antibody

Anti-Filaggrin 항체

4

(9 리뷰들)

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(41 제품이 사용된 논문 )

Anti-Filaggrin antibody (ab81468) is a rabbit polyclonal antibody detecting Filaggrin in ICC/IF. Suitable for Human.

- Over 30 publications
- Trusted since 2009
1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-Filaggrin antibody (AB81468)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Filaggrin antibody (AB81468)

ICC/IF image of ab81468 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab81468, 1/1000 dilution) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h.Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43μM.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Synthetic Peptide within Human FLG. The exact immunogen used to generate this antibody is proprietary information.

P20930

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }

제품 세부 정보

What is this antibody validated in?
Anti-Filaggrin antibody (ab81468) is a rabbit polyclonal antibody and is validated for use in Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples.

Trusted by the scientific community
Anti-Filaggrin (ab81468) was first used in a scientific publication in 2009 and has been cited over 30 times in peer-reviewed journals.

Reviewed by scientists
Anti-Filaggrin (ab81468) has over 5 independent reviews from customers.

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.
See full target information FLG

대체 명칭 보기

Filaggrin, FLG

제품이 사용된 논문 (41)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 33:e70082 PubMed40880422

2025

Re-Epithelialisation in a Yorkshire Pig Full-Thickness Excisional Wound Model Is Associated With Keratinocyte Activation, Oxidative Stress, and Biomacromolecule Oxidation.

Applications

Unspecified application

Species

Unspecified reactive species

Dylan Tinney,John T Walker,Emily Truscott,Douglas W Hamilton

Frontiers in immunology 16:1503007 PubMed40491919

2025

Rab7 inhibitor enhances stem cell differentiation into keratinocyte-like cells with anti-inflammatory properties.

Applications

Unspecified application

Species

Unspecified reactive species

Raghad Alghazali,Mouna Tabebi,Moustafa Elmasry,Ahmed El-Serafi

Journal of ginseng research 49:326-330 PubMed40453350

2025

Compound K suppresses epidermal aging induced by IL-17A treatment and UVB irradiation.

Applications

Unspecified application

Species

Unspecified reactive species

A Young Kim,Ji-Yong Jung,Donghyun Kim,Jeong Hun Cho,Yong Deog Hong,Hyoung-June Kim,Si-Young Cho

Clinical, cosmetic and investigational dermatology 18:1151-1162 PubMed40356846

2025

-Derived Exosomes Enhance Skin Barrier Integrity by Upregulating Key Barrier-Related Proteins.

Applications

Unspecified application

Species

Unspecified reactive species

Yong-Han Cho,Ji-Woo Kim,Nari Kim,Hee-Sik Kim,Jun-Hwan Jang,Jun-Tae Bae,Wanil Kim

International journal of molecular sciences 26: PubMed40076477

2025

Bulge-Derived Epithelial Cells Isolated from Human Hair Follicles Using Enzymatic Digestion or Explants Result in Comparable Tissue-Engineered Skin.

Applications

Unspecified application

Species

Unspecified reactive species

Bettina Cattier,Rina Guignard,Israël Martel,Christian Martel,Carolyne Simard-Bisson,Danielle Larouche,Béatrice Guiraud,Sandrine Bessou-Touya,Lucie Germain

Scientific reports 13:22357 PubMed38102220

2023

β-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Hyung-Su Kim,Hyoung-June Kim,Yong-Deog Hong,Eui Dong Son,Si-Young Cho

Nature communications 14:7660 PubMed37996412

2023

Vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms.

Applications

Unspecified application

Species

Unspecified reactive species

Christian Reuter,Laura Hauf,Fabian Imdahl,Rituparno Sen,Ehsan Vafadarnejad,Philipp Fey,Tamara Finger,Nicola G Jones,Heike Walles,Lars Barquist,Antoine-Emmanuel Saliba,Florian Groeber-Becker,Markus Engstler

Frontiers in immunology 14:1273182 PubMed38053996

2023

Epidermal keratinocyte-specific STAT3 deficiency aggravated atopic dermatitis-like skin inflammation in mice through TSLP upregulation.

Applications

Unspecified application

Species

Unspecified reactive species

Zhao-Yuan Wang,Yu-Xin Zheng,Fan Xu,Ying-Zhe Cui,Xue-Yan Chen,Si-Qi Chen,Bing-Xi Yan,Yuan Zhou,Min Zheng,Xiao-Yong Man

International journal of molecular sciences 24: PubMed38003573

2023

Lipids Reduce Cytokine-Induced Pro-Inflammatory Signalling and Barrier Dysfunction in Human Keratinocyte Models.

Applications

Unspecified application

Species

Unspecified reactive species

Jamie M L Kok,Georgina C Dowd,Jaydee D Cabral,Lyn M Wise

Journal of nanobiotechnology 21:354 PubMed37775761

2023

Bioinspired polydopamine nanoparticles as efficient antioxidative and anti-inflammatory enhancers against UV-induced skin damage.

Applications

Unspecified application

Species

Unspecified reactive species

Jia Zhang,Yuqi Zhou,Zhaoting Jiang,Chenhui He,Bo Wang,Qi Wang,Zeqian Wang,Tong Wu,Xiaoqi Chen,Ziwei Deng,Chunying Li,Zhe Jian
제품이 사용된 논문 모두 보기

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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