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AB236979

Anti-FILIP1L antibody

2

(1 리뷰)

|

(1 출판물)

Rabbit Polyclonal FILIP1L antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human FILIP1L aa 1-200.

대체 명칭 보기

COL4A3BPIP, DOC1, GIP90, FILIP1L, Filamin A-interacting protein 1-like, 130 kDa GPBP-interacting protein, 90 kDa GPBP-interacting protein, Protein down-regulated in ovarian cancer 1, DOC-1

4 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)

Paraffin-embedded human adrenal gland tissue stained for FILIP1L using ab236979 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)

Paraffin-embedded human colon cancer tissue stained for FILIP1L using ab236979 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)

Immunohistochemical analysis of paraffin-embedded human colon cancer tissue labelling FILIP1L with ab236979 at 1/100 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FILIP1L antibody (AB236979)

Immunohistochemical analysis of paraffin-embedded human colon tissue labelling FILIP1L with ab236979 at 1/100 dilution.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human FILIP1L aa 1-200. The exact immunogen used to generate this antibody is proprietary information.

Q4L180

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보완 제품

Primary Antibodies

AB239074

Anti-STING antibody [EPR13130-55]

20ul selling size|KO Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-STING antibody [EPR13130-55] (AB239074)

  • 0
  • 0
Primary Antibodies

AB70893

Anti-USP28 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-USP28 antibody (AB70893)

  • 0
  • 0
Primary Antibodies

AB215451

Anti-SPON2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SPON2 antibody (AB215451)

  • 0
  • 0
Primary Antibodies

AB252416

Anti-cGAS antibody [EPR23611-101]

20ul selling size|RabMAb|Recombinant

Immunoprecipitation - Anti-cGAS antibody [EPR23611-101] (AB252416)

  • 5
  • 2
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

FILIP1L also known as FILIP-1-like protein is a protein with a mass of approximately 136 kDa. Mechanically FILIP1L interacts with the actin cytoskeleton affecting cell shape and motility. It modulates cell adhesion by interacting directly with filamin A a cytoskeletal protein. FILIP1L expression occurs in various tissues including the brain heart and liver. Its presence influences cellular architecture through actin binding.
Biological function summary

FILIP1L regulates cell migration and growth. It serves as an important mediator of cellular signaling that influences cytoskeletal dynamics. Although not a part of a multi-protein complex FILIP1L's role extends to the regulation of cell division and apoptosis. It modulates responses to extracellular signals contributing to processes such as cell proliferation and differentiation. Researchers focus on FILIP1L for its dual role in promoting cellular stability and flexibility.

Pathways

FILIP1L plays critical roles in the Wnt and TGF-beta signaling pathways. It works alongside proteins like beta-catenin and SMAD2/3 to influence gene transcription related to cell cycle control and apoptosis. FILIP1L's interaction with these pathways supports its role in maintaining proper cellular communication. The pathways regulate development differentiation and homeostasis reflecting the importance of FILIP1L in broader cellular functions.

FILIP1L associates with cancer and neurological disorders. Cancer studies indicate that FILIP1L expression levels affect tumor progression linked with altered cell migration and invasion. In neurological disorders its role in the brain suggests potential involvement in conditions like neurodegenerative diseases. FILIP1L interacts with proteins such as filamin A and SMAD proteins emphasizing its involvement in both tumor biology and neural health. Understanding FILIP1L better offers insights into therapeutic strategies.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
See full target information FILIP1L
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Aging 11:10203-10219 PubMed31740625

2019

Mitochondrial fission regulator 2 (MTFR2) promotes growth, migration, invasion and tumour progression in breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Guanming Lu,Yuanhui Lai,Tiantian Wang,Weihao Lin,Jinlan Lu,Yanfei Ma,Yongcheng Chen,Haiqing Ma,Ruilei Liu,Jie Li
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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