FITC Anti-Biotin antibody

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This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Biotin acts as a fundamental component in energy production and nutrient metabolism. It forms a covalent bond with specific carboxylase enzymes like acetyl-CoA carboxylase and pyruvate carboxylase forming a protein-biotin complex. This binding allows these enzymes to perform their carboxylation reactions effectively impacting multiple metabolic pathways. Biotin also participates in gene regulation and cellular signaling processes which are essential for normal growth and development of cells.

Pathways

Biotin plays a role in fatty acid synthesis and gluconeogenesis pathways. It aids in the conversion of substrates into products necessary for storing and producing energy. For example in the fatty acid synthesis pathway biotin-dependent acetyl-CoA carboxylase catalyzes the conversion of acetyl-CoA to malonyl-CoA an important step in synthesizing fatty acids. Biotin works alongside other proteins such as holocarboxylase synthetase to ensure proper enzyme function in these pathways reflecting its interconnected role in metabolic processes.