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AB18272

FITC Anti-CD15 antibody [MEM-158]

5

(2 리뷰들)

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(2 제품이 사용된 논문 )

Anti-CD15 antibody [MEM-158] conjugated to FITC - suitable for flow cytometry, and reacts with human samples. Clone [MEM-158] is a mouse monoclonal antibody cited in 2 publications.

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Flow Cytometry - FITC Anti-CD15 antibody [MEM-158] (AB18272)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD15 antibody [MEM-158] (AB18272)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab18272 (20 μl reagent / 100 μl of peripheral whole blood).

Flow Cytometry - FITC Anti-CD15 antibody [MEM-158] (AB18272)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD15 antibody [MEM-158] (AB18272)

Separation of human neutrophil granulocytes (red-filled) from CD15 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using ab18272 (20 μl reagent / 100 μl of peripheral whole blood).

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-158

Isotype

IgM

Light chain 타입

kappa

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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대체품

Primary Antibodies

AB218403

Anti-CD15 antibody [FUT4/1478R]

Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [FUT4/1478R] (AB218403)

  • 0
  • 0
Primary Antibodies

AB17080

Anti-CD15 antibody [MMA]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [MMA] (AB17080)

  • 0
  • 0
Primary Antibodies

AB172729

Anti-CD15 antibody [EPR9521]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [EPR9521] (AB172729)

  • 0
  • 0
Primary Antibodies

AB135377

Anti-CD15 antibody [SP159]

20ul selling size|BOND RX™ Validated|Advanced Validation|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [SP159] (AB135377)

  • 5
  • 1
Primary Antibodies

AB240092

Anti-CD15 antibody [SP159] - BSA and Azide free

BOND RX™ Validated|Advanced Validation|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [SP159] - BSA and Azide free (AB240092)

  • 5
  • 1
Primary Antibodies

AB240171

Anti-CD15 antibody [EPR9521] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD15 antibody [EPR9521] - BSA and Azide free (AB240171)

  • 0
  • 0

보완 제품

Primary Antibodies

AB252126

Alexa Fluor® 488 Anti-CD133 antibody [EPR20980-104]

RabMAb|Recombinant

Flow Cytometry - Alexa Fluor® 488 Anti-CD133 antibody [EPR20980-104] (AB252126)

  • 0
  • 0
Primary Antibodies

AB182422

Anti-CD163 antibody [EPR19518]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Flow Cytometry - Anti-CD163 antibody [EPR19518] (AB182422)

  • 5
  • 17
Primary Antibodies

AB64693

Anti-CD206 antibody

BOND RX™ Validated

Western blot - Anti-CD206 antibody (AB64693)

  • 5
  • 42
Primary Antibodies

AB4223

FITC Anti-C1q antibody

Immunocytochemistry - FITC Anti-C1q antibody (AB4223)

  • 4
  • 2
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "20 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>Use 20 μl reagent / 100 μl of whole blood or 10^6 cells in a suspension.</p><p><a href='/ko/products/unavailable/fitc-mouse-igm-b117-isotype-control-ab91546'>ab91546</a> - Mouse monoclonal IgM, is suitable for use as an isotype control with this antibody.</p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 관련 사항
Purified by precipitation and chromatography
보관 버퍼
pH: 8 Preservative: 0.097% Sodium azide Constituents: BSA, PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

CD15 also known as Lewis x or 3-fucosyl-N-acetyllactosamine is a carbohydrate antigen with a molecular mass typically not individually defined due to its nature as a glycan. CD15 is expressed on the surface of many human cells including neutrophils and various epithelial cells. It is commonly associated with granulocytes and is used as a cell surface marker. The presence of CD15 can be identified using CD15 antibodies through techniques such as CD15 flow cytometry and CD15 APC labeling.
Biological function summary

CD15 is important in cell-cell interaction mechanisms. It plays a role in mediating adhesion processes particularly in immune responses where it aids neutrophils in adhering to vascular endothelium and transmigrating to sites of infection or inflammation. As a glycoconjugate CD15 forms part of a larger glycoprotein complex on the cell surface interacting with other proteins to facilitate cellular responses and movement.

Pathways

CD15's function as an adhesion molecule ties into key cellular processes such as the selectin pathway. In this pathway it interacts with proteins like E-selectin and L-selectin contributing to leukocyte rolling and extravasation during the immune response. Additionally CD15 is implicated in the signaling pathways that mediate inflammatory responses where its role in neutrophil dynamics is important.

CD15 has notable implications in Hodgkin's lymphoma and certain myeloid leukemias. It is frequently used as a diagnostic marker in these conditions where its overexpression or abnormal expression patterns may signify disease presence or progression. CD15's interaction with other proteins such as CD30 in Hodgkin's lymphoma highlights its utility in understanding the pathological mechanisms and potential therapeutic targets of these disorders.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information CD15
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Stem cell research & therapy 16:146 PubMed40128761

2025

Clusterin-mediated polarization of M2 macrophages: a mechanism of temozolomide resistance in glioblastoma stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Jianping Wen,Xia Wu,Zhicheng Shu,Dongxu Wu,Zonghua Yin,Minglong Chen,Kun Luo,Kebo Liu,Yulong Shen,Yi Le,Qingxia Shu

Journal of the neurological sciences 346:164-73 PubMed25175854

2014

Thyroid hormone-dependent epigenetic suppression of herpes simplex virus-1 gene expression and viral replication in differentiated neuroendocrine cells.

Applications

Unspecified application

Species

Unspecified reactive species

Robert W Figliozzi,Feng Chen,Matthew Balish,Amakoe Ajavon,S Victor Hsia
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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