JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB239253

FITC Anti-CD57 antibody [TB01]

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Anti-CD57 antibody [TB01] conjugated to FITC - suitable for flow cytometry, and reacts with human samples. Clone [TB01] is a mouse monoclonal antibody cited in 8 publications.

Design your panel with our interactive flow cytometry panel builder. Click here.
1 이미지
Flow Cytometry - FITC Anti-CD57 antibody [TB01] (AB239253)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-CD57 antibody [TB01] (AB239253)

Flow cytometric analysis of human peripheral blood labeling CD57 with ab239253. Surface staining. Gated on leukocytes.

관련 conjugated 항체와 다양한 조성의 항체 (2)

  • 660 APC

    APC Anti-CD57 antibody [TB01]

  • 578 PE

    PE Anti-CD57 antibody [TB01]

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

TB01

Isotype

IgM

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

대체품

Primary Antibodies

AB199156

Anti-B3GAT1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-B3GAT1 antibody (AB199156)

  • 0
  • 0
Primary Antibodies

AB203123

Anti-B3GAT1 antibody - N-terminal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-B3GAT1 antibody - N-terminal (AB203123)

  • 0
  • 0
Primary Antibodies

AB212403

Anti-CD57 antibody [HNK-1 or Leu-7] - BSA and Azide free

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD57 antibody [HNK-1 or Leu-7] - BSA and Azide free (AB212403)

  • 5
  • 1
Primary Antibodies

AB212405

Anti-CD57 antibody [NK-1] - BSA and Azide free

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD57 antibody [NK-1] - BSA and Azide free (AB212405)

  • 5
  • 2
Primary Antibodies

AB212408

Anti-CD57 antibody [NK/804] - BSA and Azide free

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD57 antibody [NK/804] - BSA and Azide free (AB212408)

  • 0
  • 0
Primary Antibodies

AB82749

Anti-CD57 antibody [NK1], prediluted

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD57 antibody [NK1], prediluted (AB82749)

  • 0
  • 0

보완 제품

Primary Antibodies

AB33273

Anti-CD57 antibody [TB01]

  • 0
  • 0
Primary Antibodies

AB134933

Anti-Granzyme B antibody [EPR8260]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Granzyme B antibody [EPR8260] (AB134933)

  • 5
  • 2
Primary Antibodies

AB270651

PE Anti-CD57 antibody [TB01]

Flow Cytometry - PE Anti-CD57 antibody [TB01] (AB270651)

  • 0
  • 0
Primary Antibodies

AB207080

Anti-Glypican 3 antibody [EPR20569]

20ul selling size|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-Glypican 3 antibody [EPR20569] (AB207080)

  • 3
  • 2
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "4 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>(or 100 μl of whole blood).</p>" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Size-exclusion chromatography
Purification 관련 사항
Purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
보관 버퍼
pH: 8 Preservative: 0.0975% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Store in the dark
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

CD57 also known as HNK-1 is a glycoprotein with a molecular weight of approximately 110 to 150 kDa. It is a marker expressed on the surface of natural killer (NK) cells T lymphocytes and some subsets of CD8+ T cells. Besides you can find this marker in neural tissue. As a surface marker CD57 is used in human immunohistochemistry (IHC) studies to identify cell populations in immune responses and has significant utility in the characterization of lymphocyte subsets.
Biological function summary

CD57 plays a role in immune regulation and cell-mediated cytotoxicity. CD57+ cells which are often mature or post-activation states in NK cells and T lymphocytes are less proliferative but have enhanced cytotoxic abilities. These cells contribute to the immune surveillance against viral infections and tumor cells. CD57 does not belong to any well-known protein complexes but can cooperate with other surface markers to modulate immune functions.

Pathways

CD57+ cell populations participate in the immune system pathways related to cell-mediated immunity and cytotoxic response. The presence of CD57 is often associated with the downregulation of proliferative pathways and the enhancement of cytotoxic pathways. It shows functional overlap with proteins such as CD16 and NKG2D which also play roles in mediating the cytotoxic activity of NK cells.

CD57 is connected to chronic infections and certain autoimmune conditions. In chronic viral infections like HIV CD57+ T cells show a state of replicative senescence where their persistent expression links to disease progression. In autoimmune disorders like rheumatoid arthritis CD57+ T cells are found in the inflamed tissues. This protein works alongside CD8 in conditions of immune dysfunction providing insights into immune status and disease activity.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

See full target information CD57

대체 명칭 보기

HKN1, LEU7
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Bone research 13:6 PubMed39800733

2025

Deep imaging of LepR stromal cells in optically cleared murine bone hemisections.

Applications

Unspecified application

Species

Unspecified reactive species

Yuehan Ni,Jiamiao Wu,Fengqi Liu,Yating Yi,Xiangjiao Meng,Xiang Gao,Luyi Xiao,Weiwei Zhou,Zexi Chen,Peng Chu,Dan Xing,Ye Yuan,Donghui Ding,Ge Shen,Min Yang,Ronjie Wu,Ling Wang,Luiza Martins Nascentes Melo,Sien Lin,Xiaoguang Cheng,Gang Li,Alpaslan Tasdogan,Jessalyn M Ubellacker,Hu Zhao,Shentong Fang,Bo Shen
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com