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AB69467

FITC Anti-Klebsiella spp antibody

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Anti-Klebsiella spp antibody conjugated to FITC is a rabbit polyclonal antibody suitable for ICC/IF, IHC-Fr.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Klebsiella pneumoniae

Applications

ICC/IF, IHC-Fr

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

ab69467 reacts with Klebsiella sp. in bacterial and infected tissue samples.

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Klebsiella pneumoniae": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1/10", "ICCIF-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "1/10 - 1/50", "IHCFr-species-notes": "<p>Fix with Acetone.</p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Klebsiella spp also known as Klebsiella species refer to a group of non-motile Gram-negative bacteria often present in various environments like soil water and plants. The cells of Klebsiella species possess a polysaccharide capsule that is an important virulence factor contributing to their pathogenic potential by protecting against phagocytosis and antimicrobial substances. They exhibit a rod-shaped morphology with a size measuring approximately 1-2 microns in length. Klebsiella spp commonly colonizes the human gastrointestinal tract and respiratory system where they can coexist without causing harm under normal circumstances.
Biological function summary

This group of bacteria functions as opportunistic pathogens often forming biofilms that contribute to their resilience and pathogenicity. Klebsiella spp play roles in nitrogen cycling as they can fix atmospheric nitrogen into ammonia benefiting their surrounding environments. This ability links them to a multi-enzyme complex facilitating processes important for nitrogen utilization and metabolism. The capsule and lipopolysaccharide layers they produce significantly enhance their survival and capability to cause infections by impeding the immune system.

Pathways

Klebsiella spp are involved in various microbial metabolic pathways notably those associated with nitrogen fixation and carbohydrate metabolism. They participate in denitrification impacting nitrogen availability in the environment and closely interact with other microbial species in these metabolic processes. Klebsiella species share interactions with proteins such as nitrogenase enzymes important for converting atmospheric nitrogen to a biologically usable form emphasizing their role in ecological and host-microbe interactions.

Klebsiella spp are associated with healthcare-associated infections like pneumonia and urinary tract infections. These bacteria frequently cause respiratory infections especially in immunocompromised individuals such as those with chronic lung disease or diabetes. They contribute to diseases by producing extended-spectrum beta-lactamases (ESBLs) enzymes that confer resistance to many beta-lactam antibiotics. Proteins like fimbriae enhance their ability to adhere to host tissues exacerbating their role in opportunistic infections.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

See full target information Klebsiella spp

대체 명칭 보기

Klebsiella

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Methods in molecular biology (Clifton, N.J.) 2071:371-409 PubMed31758463

2019

Methods for the Measurement of Early Events in Toxoplasma gondii Immunity in Mouse Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Catalina Alvarez,Ana Claudia Campos,Jonathan C Howard,Joana Loureiro,Urs Benedikt Müller,Ana Lina Rodrigues
제품이 사용된 논문 모두 보기

Product promise

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