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AB236739

Anti-FKSG14/p33 antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal FKSG14/p33 antibody. Suitable for IP, WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CENPK.

대체 명칭 보기

ICEN37, FKSG14, CENPK, Centromere protein K, CENP-K, Interphase centromere complex protein 37, Protein AF-5alpha, p33

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FKSG14/p33 antibody (AB236739)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FKSG14/p33 antibody (AB236739)

Paraffin-embedded human liver tissue stained for FKSG14/p33 using ab236739 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FKSG14/p33 antibody (AB236739)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FKSG14/p33 antibody (AB236739)

Paraffin-embedded human skin tissue stained for FKSG14/p33 using ab236739 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP, IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human CENPK.

Q9BS16

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보완 제품

Primary Antibodies

AB131259

Anti-Claudin 5 antibody [EPR7583]

RabMAb|Recombinant|20ul selling size

Western blot - Anti-Claudin 5 antibody [EPR7583] (AB131259)

  • 4
  • 7
Primary Antibodies

AB216327

Anti-Occludin antibody [EPR20992]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Occludin antibody [EPR20992] (AB216327)

  • 4
  • 7
Primary Antibodies

AB307799

Anti-ZO-1 antibody [HL1185]

Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-ZO-1 antibody [HL1185] (AB307799)

  • 1
  • 1
Primary Antibodies

AB211737

Anti-Claudin 1 antibody [EPRR18871]

20ul selling size|RabMAb|Recombinant|KO Validated

Flow Cytometry (Intracellular) - Anti-Claudin 1 antibody [EPRR18871] (AB211737)

  • 5
  • 7
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The FKSG14/p33 protein also known as Fuzzy Onions Homolog 2 or FUZ is a component involved in cellular processes like protein trafficking and vesicle transport. FKSG14 has a molecular weight of approximately 33 kDa. You often find it expressed in various tissues including neuronal and epithelial. Functionally FKSG14 plays a role in maintaining the dynamic organization of the cell through its involvement in cytoplasmic transport routes.
Biological function summary

FKSG14 participates in pathways linked to ciliogenesis and cellular asymmetry. It operates as part of the intraflagellar transport (IFT) complex which is essential in the development of primary cilia. These cilia play key roles in cell signaling and development. Presence of FKSG14 within the IFT complex underlines its importance to processes like organ lateralization and embryonic patterning. Its lack or dysfunction can disrupt normal signaling pathways critical for cellular and developmental functions.

Pathways

FKSG14 influences both the Hedgehog and Wnt signaling pathways. These pathways are important for cell differentiation and cell fate determination. Within these pathways FKSG14 interacts with proteins like Smo (Smoothened) in the Hedgehog pathway and Dvl (Disheveled) in the Wnt pathway. These relationships highlight FKSG14's involvement in complex signaling networks illustrating its key position in maintaining cellular integrity and function.

FKSG14 has links to conditions like ciliopathies and neural tube defects. Ciliopathies are disorders resulting from defects in cilia structure or function and can include polycystic kidney disease and Bardet-Biedl syndrome. FKSG14's disruption may connect with these disorders through its interaction with other ciliary proteins like IFT74. It also plays roles in neural development suggesting its involvement in neural tube defects when FKSG14 or related proteins like SHH (Sonic Hedgehog) pathways are impaired leading to congenital anomalies.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.
See full target information CENPK
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Advances in clinical and experimental medicine : official organ Wroclaw Medical University 30:691-699 PubMed34118147

2021

Upregulation of centromere protein K is crucial for lung adenocarcinoma cell viability and invasion.

Applications

Unspecified application

Species

Unspecified reactive species

Yongbo Wang,Yue Wang,Chunna Ren,Haicun Wang,Yang Zhang,Yunxia Xiu

Journal of cellular and molecular medicine : PubMed33085209

2020

Integrative analysis provides multi-omics evidence for the pathogenesis of placenta percreta.

Applications

Unspecified application

Species

Unspecified reactive species

Qingyuan Jiang,Lei Dai,Na Chen,Junshu Li,Yan Gao,Jing Zhao,Li Ding,Chengbin Xie,Xiaolian Yi,Hongxin Deng,Xiaodong Wang
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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