AB69400
Mouse Polyclonal Endonuclease V antibody. Carrier free. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 3 publications.
1 이미지
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-FLJ35220 antibody (AB69400)
ab69400 at 10μg/ml staining FLJ35220 in Hela cells by ICC/IF.
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
특성 및 보관 정보
제형
Liquid
Purification 테크닉
Affinity purification Protein G
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
제품 프로토콜
For this product, it's our understanding that no specific protocols are required. You can visit:
- Visit the General protocols
- Visit the Troubleshooting
타겟 정보
Isoform 1. Endoribonuclease that specifically cleaves inosine-containing RNAs : cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed : 23912683, PubMed : 23912718, PubMed : 25195743, PubMed : 27573237, PubMed : 31703097). Active against both single-stranded and double-stranded RNAs (PubMed : 25195743, PubMed : 31703097). Has strong preference for single-stranded RNAs (ssRNAs) toward double-stranded RNAs (dsRNAs) (PubMed : 23912718). Cleaves mRNAs and tRNAs containing inosine (PubMed : 23912683, PubMed : 31703097). Also able to cleave structure-specific dsRNA substrates containing the specific sites 5'-IIUI-3' and 5'-UIUU-3' (PubMed : 23912718, PubMed : 27573237). Inosine is present in a number of RNAs following editing; the function of inosine-specific endoribonuclease is still unclear : it could either play a regulatory role in edited RNAs, or be involved in antiviral response by removing the hyperedited long viral dsRNA genome that has undergone A-to-I editing (Probable). Binds branched DNA structures (PubMed : 23139746).. Isoform 6. Endoribonuclease that specifically cleaves inosine-containing RNAs : cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed : 31703097). Active against both single-stranded and double-stranded RNAs (PubMed : 31703097). Cleaves tRNAs containing inosine (PubMed : 31703097).. Isoform 7. Endoribonuclease that specifically cleaves inosine-containing RNAs : cleaves RNA at the second phosphodiester bond 3' to inosine (PubMed : 31703097). Active against both single-stranded and double-stranded RNAs (PubMed : 31703097). Cleaves tRNAs containing inosine (PubMed : 31703097).
대체 명칭 보기
Endonuclease V, hEndoV, Inosine-specific endoribonuclease, ENDOV
제품이 사용된 논문 (3)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Journal of the American Heart Association 10:e020656 PubMed34259011
2021
Regulates Atherosclerosis Through C-C Motif Chemokine Ligand 2-Mediated Monocyte Infiltration.
Applications
Unspecified application
Species
Unspecified reactive species
Xiang Yi Kong,Camilla Huse,Kuan Yang,Jonas Øgaard,Natalia Berges,Erik Sebastian Vik,Meh Sameen Nawaz,Ana Quiles-Jiménez,Azhar Abbas,Ida Gregersen,Sverre Holm,Vigdis Bjerkli,Azita Rashidi,Cathrine Fladeby,Rajikala Suganthan,Ellen Lund Sagen,Mona Skjelland,Anna Lång,Stig Ove Bøe,Magnar Bjørås,Pål Aukrust,Ingrun Alseth,Bente Halvorsen,Tuva Børresdatter Dahl
PloS one 14:e0225081 PubMed31703097
2019
Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform.
Applications
Unspecified application
Species
Unspecified reactive species
Natalia Berges,Meh Sameen Nawaz,Tuva Børresdatter Dahl,Lars Hagen,Magnar Bjørås,Jon K Laerdahl,Ingrun Alseth
The Journal of biological chemistry 291:21786-21801 PubMed27573237
2016
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules.
Applications
Unspecified application
Species
Unspecified reactive species
Meh Sameen Nawaz,Erik Sebastian Vik,Natalia Berges,Cathrine Fladeby,Magnar Bjørås,Bjørn Dalhus,Ingrun Alseth
Product promise
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