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AB236385

Anti-FOXN2 antibody [OTI5H8]

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Mouse Monoclonal FOXN2 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FOXN2.

대체 명칭 보기

HTLF, FOXN2, Forkhead box protein N2, Human T-cell leukemia virus enhancer factor

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

OTI5H8

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human FOXN2.

P32314

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보완 제품

Primary Antibodies

AB275378

Anti-KAT3B / p300 antibody [EPR23495-268] - ChIP Grade

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Immunocytochemistry/ Immunofluorescence - Anti-KAT3B / p300 antibody [EPR23495-268] - ChIP Grade (AB275378)

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Primary Antibodies

AB195352

Anti-METTL3 antibody [EPR18810]

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Immunohistochemistry - Anti-METTL3 antibody [EPR18810] (AB195352)

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Primary Antibodies

AB40772

Anti-E Cadherin antibody [EP700Y] - Intercellular Junction Marker

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Western blot - Anti-E Cadherin antibody [EP700Y] - Intercellular Junction Marker (AB40772)

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Primary Antibodies

AB220163

Anti-YTHDF2 antibody [EPR20318]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunoprecipitation - Anti-YTHDF2 antibody [EPR20318] (AB220163)

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  • 3
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
Purification 관련 사항
Purified from cell culture supernatant.
보관 버퍼
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

FOXN2 also known as Forkhead Box N2 represents a transcription factor that regulates gene expression. The protein has a mass of approximately 59 kDa and contains a DNA-binding domain known as the Forkhead domain. Researchers have observed FOXN2 expression across various tissues indicating its widespread biological function. Though FOXN2 does not have many popular aliases it plays significant role in cellular processes.
Biological function summary

FOXN2 influences development and cellular differentiation. It acts as a part of the regulation network for gene expression though it does not form a stable complex with other proteins. FOXN2 plays a role in cell cycle regulation where it controls specific target genes necessary for proliferation and development. This control extends to pathways that modulate cellular growth and differentiation.

Pathways

FOXN2 integrates into the broader network of transcriptional regulation in cellular development and differentiation. FOXN2 participates in the Wnt signaling pathway important for controlling cell fate determination. It also interacts with key proteins like β-catenin which links it to cellular growth processes. This connection allows FOXN2 to affect major signaling cascades contributing to normal development.

Abnormalities in FOXN2 function can lead to developmental disorders and cancers. Genetic mutations affecting FOXN2 have connections to certain types of cancer like breast cancer where it may influence tumor formation and progression. Research shows that FOXN2 interacts with proteins such as BRCA1 which further ties its dysregulation to cancer susceptibility. Understanding FOXN2 helps in developing potential therapeutic targets for these diseases.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Binds to the purine-rich region in HTLV-I LTR.
See full target information FOXN2
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Dose-response : a publication of International Hormesis Society 17:1559325819886766 PubMed31762715

2019

mRNA and lncRNA Expression Profiling of Radiation-Induced Gastric Injury Reveals Potential Radiation-Responsive Transcription Factors.

Applications

Unspecified application

Species

Unspecified reactive species

Guangxia Chen,Yang Feng,Zhiqiang Sun,Yiying Gao,Chuannan Wu,Haihan Zhang,Jinming Cao,Zhuo Chen,Jianping Cao,Yaqun Zhu,Shuyu Zhang
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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