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AB181185

Anti-FP100 antibody [EPR13721]

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(1 출판물)

Rabbit Recombinant Monoclonal FP100 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

대체 명칭 보기

C17orf70, FAAP100, Fanconi anemia core complex-associated protein 100, Fanconi anemia-associated protein of 100 kDa

1 이미지
Western blot - Anti-FP100 antibody [EPR13721] (AB181185)
  • WB

Supplier Data

Western blot - Anti-FP100 antibody [EPR13721] (AB181185)

All lanes:

Western blot - Anti-FP100 antibody [EPR13721] (ab181185) at 1/1000 dilution

Lane 1:

Hela cell lysate at 20 µg

Lane 2:

Jurkat cell lysate at 20 µg

Lane 3:

HepG2 cell lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 93 kDa

Observed band size: 93 kDa

false

관련 conjugated 항체와 다양한 조성의 항체 (1)

  • Carrier free

    Anti-FP100 antibody [EPR13721] - BSA and Azide free

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13721

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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대체품

Primary Antibodies

AB180157

Anti-FP100 antibody [EPR13721-22] - C-terminal

RabMAb|Recombinant

Western blot - Anti-FP100 antibody [EPR13721-22] - C-terminal (AB180157)

  • 0
  • 0

보완 제품

Primary Antibodies

AB5065

Anti-FANCC antibody

Immunocytochemistry/ Immunofluorescence - Anti-FANCC antibody (AB5065)

  • 4
  • 6
Primary Antibodies

AB272618

Anti-FANCL antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FANCL antibody (AB272618)

  • 0
  • 0
Primary Antibodies

AB75328

Anti-REV1 antibody

  • 0
  • 1
Primary Antibodies

AB122473

Anti-WDR48/UAF1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WDR48/UAF1 antibody (AB122473)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>" } } }
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제품 세부 정보

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형
Liquid
Purity
Tissue culture supernatant
보관 버퍼
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
배송 시 보관 조건
Conditional Ambient
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

FP100 also known by some researchers as Protein Zeta has a molecular mass of approximately 50 kDa. It is an intracellular protein that can be found mostly in the cytoplasm of immune cells including macrophages and dendritic cells. The protein serves as an adapter that interacts with multiple signaling molecules. By doing this it helps facilitate the assembly of protein complexes that are essential for downstream signal transmission.
Biological function summary

This protein enables efficient immune cell communication in response to external stimuli. FP100 acts as a scaffold in forming complexes that promote signaling pathways important for immune response activation. It interacts with kinases and phosphatases to regulate signal transduction processes that are responsible for initiating cell activation proliferation and survival.

Pathways

FP100 is an important participant in the NF-kB and MAPK signaling pathways. These pathways play an important role in mediating inflammatory responses and cell survival. FP100 connects with proteins like IKK-beta in the NF-kB pathway and MEK1/2 in the MAPK pathway assisting in modulating responses to infections or cellular stress.

Variations or dysregulation of FP100 activity relate closely to autoimmune conditions and chronic inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease. Its interaction with proteins like TNF-alpha and interleukin-6 places FP100 at a strategic position influencing the pathological progression of these disorders making it a potential therapeutic target for intervention.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Plays a role in Fanconi anemia-associated DNA damage response network. Regulates FANCD2 monoubiquitination and the stability of the FA core complex. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed.
See full target information FAAP100
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

iScience 26:106417 PubMed37153444

2023

Ultra-rare complement factor 8 coding variants in families with age-related macular degeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Lina Zelinger,Tammy M Martin,Jayshree Advani,Laura Campello,Milton A English,Alan Kwong,Claire Weber,Jennifer Maykoski,Yuri V Sergeev,Robert Fariss,Emily Y Chew,Michael L Klein,Anand Swaroop
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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