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AB235526

Anti-GALNT14 antibody

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Rabbit Polyclonal GALNT14 antibody. Suitable for WB, IHC-P and reacts with Rat, Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human GALNT14.

대체 명칭 보기

UNQ2434/PRO4994, GALNT14, Polypeptide N-acetylgalactosaminyltransferase 14, Polypeptide GalNAc transferase 14, Protein-UDP acetylgalactosaminyltransferase 14, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14, GalNAc-T14, pp-GaNTase 14

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALNT14 antibody (AB235526)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALNT14 antibody (AB235526)

Paraffin-embedded human small intestine tissue stained for GALNT14 using ab235526 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Full Length Protein corresponding to Human GALNT14.

Q96FL9

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보완 제품

Proteins & Peptides

AB316446

Recombinant Human Mucin 5AC Protein Standard (His tag)

Sandwich ELISA - Recombinant Human Mucin 5AC Protein Standard (His tag) (AB316446)

  • 0
  • 0
Proteins & Peptides

AB276585

Recombinant Human GALNT2 protein (His tag)

SDS-PAGE - Recombinant Human GALNT2 protein (His tag) (AB276585)

  • 0
  • 0
Primary Antibodies

AB201196

Anti-GALNT12 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GALNT12 antibody (AB201196)

  • 0
  • 0
Primary Antibodies

AB106471

Anti-GALNT10 antibody

Immunocytochemistry/ Immunofluorescence - Anti-GALNT10 antibody (AB106471)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

GALNT14 also known as polypeptide N-acetylgalactosaminyltransferase 14 is an enzyme that initiates O-linked glycosylation by transferring N-acetylgalactosamine (GalNAc) to serine or threonine residues on proteins. It has a molecular weight of approximately 66 kDa. This enzyme is mainly expressed in tissues such as the stomach colon and central nervous system. GALNT14 plays a part in the vast network of glycosylation enzymes essential for protein modification.
Biological function summary

GALNT14 modifies proteins by adding sugar moieties which affects the protein's stability signaling and interactions. It contributes to the extracellular matrix and cellular signaling networks. This enzyme is also not part of any defined complex but operates independently to modify and influence proteins post-translationally. Glycosylation processes such as those mediated by GALNT14 are integral to cell-cell communication and immune responses.

Pathways

GALNT14 integrates into the glycoprotein synthesis and modification pathways. It is involved mainly in the mucin-type O-glycosylation pathway which influences various functions like cell adhesion. In this pathway it interacts or is related to other glycosyltransferases including GALNT7 to orchestrate these modification processes. These pathways ensure proper protein trafficking and function which are fundamental for healthy cell development and differentiation.

The aberrant expression of GALNT14 has links to cancer particularly gastric and colorectal cancers. Alterations in glycosylation impact cell surface proteins which can contribute to tumor formation and metastasis. It has connections to MUC1 a protein whose abnormal glycosylation and resulting function have implications in cancer progression. Evaluating GALNT14 expression might provide insights into prognostic markers or therapeutic targets for these conditions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Displays activity toward mucin-derived peptide substrates such as Muc2, Muc5AC, Muc7, and Muc13 (-58). May be involved in O-glycosylation in kidney.
See full target information GALNT14
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cancer medicine 12:5035-5054 PubMed36205357

2022

Systemic analysis of the DNA replication regulator origin recognition complex in lung adenocarcinomas identifies prognostic and expression significance.

Applications

Unspecified application

Species

Unspecified reactive species

Min Tang,Juan Chen,Tian Zeng,Dong-Mei Ye,Yu-Kun Li,Juan Zou,Yu-Ping Zhang
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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