AB236974

Anti-GLT8D1 antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal GLT8D1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human GLT8D1 aa 1-350.

대체 명칭 보기

GALA4A, AD-017, MSTP137, UNQ572/PRO1134, GLT8D1, Glycosyltransferase 8 domain-containing protein 1

4 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)

Paraffin-embedded human kidney tissue stained for GLT8D1 using ab236974 at 1/100 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)

PC-3 (Human prostate adenocarcinoma cell line) cells stained for GLT8D1 (green) using ab236974 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488^® conjugated Goat Anti-Rabbit IgG (H+L).

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)

HepG2 (Human liver hepatocellular carcinoma cell line) cells stained for GLT8D1 (green) using ab236974 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488^® conjugated Goat Anti-Rabbit IgG (H+L).

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)

Paraffin-embedded human liver tissue stained for GLT8D1 using ab236974 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

WB, ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human GLT8D1 aa 1-350. The exact immunogen used to generate this antibody is proprietary information.

Q68CQ7

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein G

Purification 관련 사항

Purity >95%.

보관 버퍼

pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

GLT8D1 also known as Glycosyltransferase 8 domain containing 1 is an enzyme that participates in glycosylation catalyzing the addition of sugars to proteins or lipids. The protein has a mass of approximately 46 kDa. GLT8D1 expression occurs widely including in tissues like the liver and brain. This expression pattern suggests GLT8D1 plays several important roles in various physiological processes.

Biological function summary

GLT8D1 contributes to the modification and stability of proteins. It is not currently recognized as part of a larger complex but interacts within cellular mechanisms to maintain protein function. The enzyme affects cell signaling and communication by modifying surface proteins impacting processes such as development and immune response.

Pathways

GLT8D1 is involved in the protein glycosylation pathway contributing to the modification of glycoproteins. This pathway plays a role in proteostasis affecting quality control of proteins. GLT8D1 might work alongside other glycosyltransferases such as MGATs which also participate in protein modification although specific direct interactions might not be well-characterized.

GLT8D1 mutations or altered activity have been associated with certain neurodegenerative conditions such as spinocerebellar ataxia. In these diseases disruptions in glycosylation processes might impact overall neuronal function and stability. GLT8D1 might also engage indirectly with proteins like ataxin which participate in related pathways affecting neuronal health and disease progression.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

In vitro, catalyzes the transfer of a galactose residue from UDP-galactose onto GalNAc and GlcNAc structures.

See full target information GLT8D1

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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in immunology 13:907636 PubMed35967419

2022

Spindle pole body component 25 and platelet-derived growth factor mediate crosstalk between tumor-associated macrophages and prostate cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Feilun Cui,Zhipeng Xu,Jianpeng Hu,Yumei Lv

Cell death and differentiation 29:1834-1849 PubMed35301431

2022

Hypoxia-induced GLT8D1 promotes glioma stem cell maintenance by inhibiting CD133 degradation through N-linked glycosylation.

Applications

Unspecified application

Species

Unspecified reactive species

Kun Liu,Liping Jiang,Yulin Shi,Baiyang Liu,Yaomei He,Qiushuo Shen,Xiulin Jiang,Zhi Nie,Jun Pu,Cuiping Yang,Yongbin Chen

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-GLT8D1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (2)

Product promise