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AB75499

Anti-GPRC5C antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal GPRC5C antibody. Suitable for WB and reacts with African green monkey, Mouse samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human GPRC5C.
1 이미지
Western blot - Anti-GPRC5C antibody (AB75499)
  • WB

Unknown

Western blot - Anti-GPRC5C antibody (AB75499)

All lanes:

Western blot - Anti-GPRC5C antibody (ab75499) at 1/500 dilution

Lane 1:

RAW264.7 cell extract at 30 µg

Lane 2:

Cos-7 cell extract at 30 µg

Lane 3:

RAW264.7 cell extract at 30 µg with immunising peptide

Predicted band size: 48 kDa

Observed band size: 100 kDa,48 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, African green monkey

Applications

WB

applications

Immunogen

Synthetic Peptide within Human GPRC5C. The exact immunogen used to generate this antibody is proprietary information.

Q9NQ84

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보완 제품

Primary Antibodies

AB271042

Anti-IL-6R antibody [EPR24322-143]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-6R antibody [EPR24322-143] (AB271042)

  • 5
  • 1
Primary Antibodies

AB236630

Anti-CD9 antibody [EPR23105-121]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD9 antibody [EPR23105-121] (AB236630)

  • 5
  • 4
Primary Antibodies

AB203220

Anti-CD134 / OX40L receptor antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD134 / OX40L receptor antibody (AB203220)

  • 5
  • 3
Primary Antibodies

AB218810

Anti-CD47 antibody [EPR21794]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD47 antibody [EPR21794] (AB218810)

  • 5
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "African green monkey": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

GPRC5C also known as G protein-coupled receptor family C group 5 member C acts as a cell surface receptor involved in various signaling processes. Weighing approximately 42 kilodaltons (kDa) this receptor is expressed in several human tissues including the lung kidney and liver. GPRC5C belongs to the group of G protein-coupled receptors which are important for mediating the effects of diverse extracellular signals into cellular responses.
Biological function summary

The function of GPRC5C involves interaction with G proteins to transmit signals within cells. The receptor does not operate in isolation but may form part of larger signaling complexes. Through its signaling activities GPRC5C can influence cellular processes such as growth and differentiation. Its expression pattern suggests roles in both normal physiological processes and in responses to environmental changes.

Pathways

Proteins like GPRC5C participate in important processes like cell survival and proliferation. It intersects the MAPK (mitogen-activated protein kinase) pathway an important signaling cascade for cellular growth responses. In this pathway GPRC5C can interact with proteins such as ERK (extracellular signal-regulated kinase) and other G proteins to modulate cell signaling dynamics affecting how cells respond to external stimuli.

Alterations in GPRC5C expression or function link to cancer and inflammatory diseases. Aberrant signaling through GPRC5C can contribute to uncontrolled cell growth characteristic in certain cancers with proteins like ERK playing complementary roles in these processes. Additionally improper GPRC5C activity may influence inflammatory pathways associating it with conditions where immune responses become dysregulated. Understanding GPRC5C's role in disease may offer therapeutic insights and intervention strategies.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
See full target information GPRC5C

대체 명칭 보기

RAIG3, PSEC0087, GPRC5C, G-protein coupled receptor family C group 5 member C, Retinoic acid-induced gene 3 protein, RAIG-3
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Bone 176:116866 PubMed37558192

2023

G-protein coupled receptor 5C (GPRC5C) is required for osteoblast differentiation and responds to EZH2 inhibition and multiple osteogenic signals.

Applications

Unspecified application

Species

Unspecified reactive species

Parisa Dashti,Roman Thaler,John R Hawse,M Lizeth Galvan,Bram J van der Eerden,Andre J van Wijnen,Amel Dudakovic

International journal of molecular sciences 24: PubMed37240083

2023

AEC and AFMSC Transplantation Preserves Fertility of Experimentally Induced Rat Varicocele by Expressing Differential Regenerative Mechanisms.

Applications

Unspecified application

Species

Unspecified reactive species

Alessia Peserico,Barbara Barboni,Valentina Russo,Delia Nardinocchi,Maura Turriani,Costanza Cimini,Nicola Bernabò,Ornella Parolini,Antonietta Rosa Silini,Ivana Antonucci,Liborio Stuppia,Paolo Berardinelli,Ilaria Falanga,Davide Perruzza,Luca Valbonetti,Annunziata Mauro
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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