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AB196770

Anti-GTF2A1 antibody

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Rabbit Polyclonal GTF2A1 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human GTF2A1.

대체 명칭 보기

TF2A1, GTF2A1, Transcription initiation factor IIA subunit 1, General transcription factor IIA subunit 1, TFIIAL, Transcription initiation factor TFIIA 42 kDa subunit, TFIIA-42

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GTF2A1 antibody (AB196770)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GTF2A1 antibody (AB196770)

Immunohistochemical analysis of Human thyroid cancer tissue labeling GTF2A1 with ab196770 at 1/50.

Western blot - Anti-GTF2A1 antibody (AB196770)
  • WB

Supplier Data

Western blot - Anti-GTF2A1 antibody (AB196770)

All lanes:

Western blot - Anti-GTF2A1 antibody (ab196770) at 1/500 dilution

Lane 1:

Mouse liver extract

Lane 2:

Mouse heart extract

Predicted band size: 42 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human GTF2A1. The exact immunogen used to generate this antibody is proprietary information.

P52655

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보완 제품

Primary Antibodies

AB194951

Anti-TRAP100/MED24 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TRAP100/MED24 antibody (AB194951)

  • 0
  • 0
Primary Antibodies

AB130996

Anti-THRAP5 antibody

Immunoprecipitation - Anti-THRAP5 antibody (AB130996)

  • 5
  • 1
Primary Antibodies

AB259957

Anti-RBBP7 antibody [EPR23796-74] - ChIP Grade

20ul selling size|BOND RX™ Validated|RabMAb|Advanced Validation|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RBBP7 antibody [EPR23796-74] - ChIP Grade (AB259957)

  • 0
  • 0
Primary Antibodies

AB252922

Anti-CD36 antibody [EPR22509-40]

RabMAb|Recombinant|20ul selling size

Flow Cytometry - Anti-CD36 antibody [EPR22509-40] (AB252922)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

GTF2A1 also known as general transcription factor IIA is a protein involved in the initiation of transcription by RNA polymerase II. It interacts directly with the TATA-binding protein (TBP) and stabilizes the formation of the transcription preinitiation complex. GTF2A1 has a molecular mass of approximately 35 kDa. Researchers identify its expression in various tissues meaning it likely plays a broad role in gene regulation in different cell types.
Biological function summary

GTF2A1 assists in the accurate transcription start site selection and transcription regulation. This protein often associates with TBP and other transcription factors such as TFIIE and TFIIF forming part of the transcription preinitiation complex. It helps enhance the affinity of TBP for the TATA box a critical component in transcription initiation.

Pathways

Transcription factor GTF2A1 participates in the transcriptional regulation process. It interacts significantly within the general RNA polymerase II transcription machinery and influences pathways like the Wnt signaling pathway. GTF2A1 works closely with TFIIE and other general transcription factors in these pathways to regulate gene expression.

Researchers have implicated abnormal GTF2A1 activity in certain types of cancer and developmental disorders. Its interaction with TBP and related transcription factors means that disruptions in its function could lead to aberrant gene expression contributing to the progression of these diseases. Monitoring GTF2A1 and associated proteins may provide insight into therapeutic targets for these conditions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.
See full target information GTF2A1
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of breast cancer 22:172-184 PubMed31281721

2019

Overexpression of Tumor Protein p53-regulated Apoptosis-inducing Protein 1 Regulates Proliferation and Apoptosis of Breast Cancer Cells through the PI3K/Akt Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yueyang Liang,Shushu Wang,Jia Liu
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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