Mouse Monoclonal HADH antibody. Suitable for IP, Flow Cyt, IHC-P, ICC/IF and reacts with Human samples. Cited in 3 publications.
대체 명칭 보기
HAD, HAD1, HADHSC, SCHAD, HADH, HCDH, Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase, Short-chain 3-hydroxyacyl-CoA dehydrogenase
- ICC/IF
Unknown
Immunocytochemistry/ Immunofluorescence - Anti-HADH antibody [1A12BC8] (AB110284)
MRC5 fibroblasts labeled with ab110284 at 5μg/ml and stained with Texas Red conjugated to goat anti-mouse secondary.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HADH antibody [1A12BC8] (AB110284)
ab110284, at 1/250 dilution, staining HADH in formalin-fixed, paraffin-embedded Human cerebellum by Immunohistochemistry. HADH immunoactivity is most intense in neuronal cell bodies, most notably in the large Purkinje cells.
- Flow Cyt
Unknown
Flow Cytometry - Anti-HADH antibody [1A12BC8] (AB110284)
HL-60 cells were stained with 1 µg/ml ab110284 (blue) or an equal amount of an isotype control antibody (red) and analyzed by flow cytometry.
- IP
Unknown
Immunoprecipitation - Anti-HADH antibody [1A12BC8] (AB110284)
HADH immunocaptured from Human liver mitochondria using ab110284.
All lanes:
Immunoprecipitation - Anti-HADH antibody [1A12BC8] (ab110284)
Predicted band size: 34 kDa
false
Reactivity 정보
제품 세부 정보
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com
특성 및 보관 정보
제형
Purification 테크닉
Purification 관련 사항
보관 버퍼
배송 시 보관 조건
적절한 단기 보관 조건
적절한 장기 보관 조건
보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The HADH enzyme holds significant responsibility for mitochondrial fatty acid oxidation. It plays a role in the degradation of medium and short-chain fatty acids. As part of a larger enzyme complex it works integrally with other dehydrogenases to maintain cellular energy levels and metabolic homeostasis especially during fasting or periods of increased energy demand.
Pathways
HADH functions prominently in the beta-oxidation pathway of fatty acid metabolism. This enzyme works in conjunction with acyl-CoA dehydrogenases further highlighting its role in breaking down fatty acids into acetyl-CoA an important molecule for energy production in the citric acid cycle. The activity of HADH interacts closely with other mitochondrial enzymes to maintain efficient energy turnover.
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타겟 정보
제품이 사용된 논문 (3)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Frontiers in immunology 14:1324205 PubMed38090559
2023
Applications
Unspecified application
Species
Unspecified reactive species
Molecular medicine reports 27: PubMed36562355
2022
Applications
Unspecified application
Species
Unspecified reactive species
Cell death & disease 13:912 PubMed36309482
2022
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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