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AB238319

Anti-hCG antibody [RM330]

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(4 제품이 사용된 논문 )

Rabbit Monoclonal GLHA antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human CGA.

대체 명칭 보기

Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain, Luteinizing hormone alpha chain, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, Thyrotropin alpha chain, CG-alpha, FSH-alpha, LSH-alpha, TSH-alpha, CGA, Anterior pituitary glycoprotein hormones common subunit alpha, CG-ALPHA, CGB, CGB5, Choriogonadotropin alpha chain, Chorionic gonadotrophin chain beta, Chorionic gonadotropin beta chain, Chorionic gonadotropin beta subunit, FSH A, FSH-alpha, Follitropin alpha chain, GPHA 1, GPHa, Glycoprotein hormones alpha chain, HCG, Human Chorionic Gonadotropin, LHA, LSH-alpha, Luteinizing hormone alpha chain, Lutropin alpha chain, TSH-alpha, TSHA, Thyroid stimulating hormone alpha chain, Thyrotropin alpha chain, chorionic gonadotrophin subunit alpha, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin, alpha polypeptide, chorionic gonadotropin, beta polypeptide, chorionic gonadotropin, beta polypeptide 3, follicle-stimulating hormone alpha chain, follicle-stimulating hormone alpha subunit, glycoprotein hormones, alpha polypeptide, hCGB

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG antibody [RM330] (AB238319)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG antibody [RM330] (AB238319)

Formalin-fixed, paraffin-embedded human placenta tissue stained for hGC using ab238319 at 1/1000 dilution in immunohistochemical analysis.

Western blot - Anti-hCG antibody [RM330] (AB238319)
  • WB

Supplier Data

Western blot - Anti-hCG antibody [RM330] (AB238319)

All lanes:

Western blot - Anti-hCG antibody [RM330] (ab238319) at 1/20000 dilution

All lanes:

Native hGC purified from human urine

Predicted band size: 18 kDa

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주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

RM330

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Native Full Length Protein corresponding to Human CGA.

P01215

Specificity

ab238319 reacts to hCG. The antibody recognizes both the native complex and the β subunit of hCG.

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대체품

Primary Antibodies

AB54410

Anti-hCG antibody

Western blot - Anti-hCG antibody (AB54410)

  • 0
  • 0
Primary Antibodies

AB9376

Anti-hCG antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG antibody (AB9376)

  • 5
  • 1
Primary Antibodies

AB400

Anti-hCG antibody [HCG1]

  • 1
  • 1
Primary Antibodies

AB8466

Anti-hCG antibody [2092]

  • 0
  • 0

보완 제품

Assay Kits

AB272194

Human CG beta ELISA Kit (CGB3)

Recombinant|SimpleStep

Sandwich ELISA - Human CG beta ELISA Kit (CGB3) (AB272194)

  • 0
  • 0
Primary Antibodies

AB131170

Anti-hCG beta antibody [EPHCGR2]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG beta antibody [EPHCGR2] (AB131170)

  • 0
  • 0
Primary Antibodies

AB32072

Anti-c-Myc antibody [Y69] - ChIP Grade

BOND RX™ Validated|KO Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-c-Myc antibody [Y69] - ChIP Grade (AB32072)

  • 4
  • 56
Primary Antibodies

AB82157

Anti-liver FABP antibody [2G4]

Western blot - Anti-liver FABP antibody [2G4] (AB82157)

  • 0
  • 0
Primary Antibodies

AB191077

Anti-Nkx2.2 antibody [EPR14638] - N-terminal

BOND RX™ Validated|RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Nkx2.2 antibody [EPR14638] - N-terminal (AB191077)

  • 5
  • 4
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/5000 - 1/20000", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
Purification 관련 사항
Purified from an animal origin–free culture supernatant.
보관 버퍼
Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Human chorionic gonadotropin (hCG) is a glycoprotein hormone composed of two subunits alpha and beta. The beta subunit confers its specific biological activity. Its molecular weight ranges around 36.7 kDa. hCG is produced in the placenta during pregnancy and is also expressed in pituitary cells. Known alternatively as the pregnancy hormone hCG plays a critical role in maintaining the luteal function during the early stages of pregnancy.
Biological function summary

HCG regulates several functions related to reproduction. It supports the corpus luteum in ovaries to secrete progesterone during early pregnancy contributing to the uterine lining's maintenance. Moreover hCG can interact with the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) indicating its involvement in broader reproductive functions. Not as well known hCG may exist in various forms such as hCG intact influencing certain biological pathways differently.

Pathways

Scientists study hCG's role in reproductive signaling and gonadotropin pathways. It interacts closely with luteinizing hormone (LH) with substantial overlap in their pathway functions impacting reproductive health and fertility cycles. hCG's activation of specific receptors like LHCGR plays a role in these pathways connecting it to various fertility-related responses in the human body.

HCG levels can be an indicative marker for certain conditions. Elevated hCG levels may signal trophoblastic diseases such as molar pregnancy or gestational trophoblastic neoplasia. Its abnormal expression might also indicate testicular cancer where it acts as a tumor marker. Both conditions relate to hCG through its shared glycoprotein structure with other hormones like thyroid-stimulating hormone (TSH) which links the hormone to broader endocrine disorder research.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
See full target information CGA
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제품이 사용된 논문 (4)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of cachexia, sarcopenia and muscle 16:e13734 PubMed39971710

2025

SIRT6 Ameliorates Cancer Cachexia-Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Kang Xu,Yida Wang,Fang Wang,Yannan Guo,Yu Ren,Vivien Low,Sungyun Cho,Qingfei Liu,Ying Qiu,Xue Li,Kang Yu,Zhongchi Li,Zhao Wang

Heliyon 10:e24499 PubMed38298727

2024

CPY27B1-related vitamin D deficiency contributes to the impaired function of CD4T cells in Recurrent spontaneous miscarriage.

Applications

Unspecified application

Species

Unspecified reactive species

Chaoyan Yue,Yanhui Ma,Mingyan Wang,Minmin Yuan,Yi Meng,Zhiheng Wang,Chunmei Ying

Frontiers in cell and developmental biology 11:1167097 PubMed37250894

2023

Metformin impairs trophoblast metabolism and differentiation in a dose-dependent manner.

Applications

Unspecified application

Species

Unspecified reactive species

Sereen K Nashif,Renee M Mahr,Snehalata Jena,Seokwon Jo,Alisa B Nelson,Danielle Sadowski,Peter A Crawford,Patrycja Puchalska,Emilyn U Alejandro,Micah D Gearhart,Sarah A Wernimont

Scientific reports 13:7387 PubMed37149697

2023

Mitochondrial citrate metabolism and efflux regulate BeWo differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Renee M Mahr,Snehalata Jena,Sereen K Nashif,Alisa B Nelson,Adam J Rauckhorst,Ferrol I Rome,Ryan D Sheldon,Curtis C Hughey,Patrycja Puchalska,Micah D Gearhart,Eric B Taylor,Peter A Crawford,Sarah A Wernimont
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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