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AB27622

HRP Anti-Apolipoprotein B antibody

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(3 제품이 사용된 논문 )

Anti-Apolipoprotein B antibody conjugated to HRP is a goat polyclonal antibody suitable for ELISA, Western blot, and reacts with human samples.

주요 정보

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Excitation/Emission
Carrier free

No

Reacts with

Human

Applications

WB, ELISA

applications

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대체품

Primary Antibodies

AB27637

FITC Anti-Apolipoprotein B antibody

  • 0
  • 0
Primary Antibodies

AB7616

Anti-Apolipoprotein B antibody

Western blot - Anti-Apolipoprotein B antibody (AB7616)

  • 4
  • 2
Primary Antibodies

AB20737

Anti-Apolipoprotein B antibody

  • 4
  • 6
Primary Antibodies

AB139401

Anti-Apolipoprotein B antibody [EPR2914]

20ul selling size|RabMAb|Recombinant

Western blot - Anti-Apolipoprotein B antibody [EPR2914] (AB139401)

  • 0
  • 0
Primary Antibodies

AB231683

Anti-Apolipoprotein B antibody [EPR2914] - BSA and Azide free

RabMAb|Recombinant

Western blot - Anti-Apolipoprotein B antibody [EPR2914] - BSA and Azide free (AB231683)

  • 0
  • 0

보완 제품

Assay Kits

AB65390

Cholesterol Assay Kit - HDL and LDL/VLDL

Biochemical assay - Cholesterol Assay Kit - HDL and LDL/VLDL (AB65390)

  • 4
  • 10
Primary Antibodies

AB242565

Anti-Lipoprotein a antibody [EPR19731-148] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-Lipoprotein a antibody [EPR19731-148] - BSA and Azide free (Capture) (AB242565)

  • 0
  • 0
Assay Kits

AB212165

Human Lipoprotein A ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human Lipoprotein A ELISA Kit (AB212165)

  • 5
  • 1
Assay Kits

AB230932

Mouse Apo B ELISA Kit

Recombinant|SimpleStep

ELISA - Mouse Apo B ELISA Kit (AB230932)

  • 0
  • 0
Primary Antibodies

AB7613

Anti-Apolipoprotein A I antibody

  • 3
  • 3
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Reactivity 정보

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제품 세부 정보

What is this antibody validated in?
HRP Anti-Apolipoprotein B antibody (ab27622) is a goat polyclonal antibody and is validated for use in Western Blot (WB), ELISA in Human samples.
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
Purification 관련 사항
Purified by human apo B-100-Sepharose™ affinity column.
보관 버퍼
pH: 6.5 - 7.4 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 1% BSA, 0.58% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Apolipoprotein B often referred to as ApoB is a core protein component of low-density lipoproteins (LDL) and is essential for their assembly and secretion. ApoB is also known as apolipoproteine B and apolipoprotein B protein. This protein has a large molecular weight approximately 550 kDa. ApoB is primarily expressed in the liver and to some extent in the intestine. Its large size allows it to provide structural integrity to lipoprotein particles playing a role in lipid metabolism.
Biological function summary

ApoB plays a significant role in lipid transport and metabolism. It is a critical component of the lipoprotein particle complex which is responsible for the transport of lipids such as cholesterol and triglycerides through the bloodstream. ApoB helps in the binding of lipoproteins to cell receptors facilitating the uptake of lipids by tissues. Its presence on the surface of lipoproteins makes it important for normal cholesterol homeostasis in the human body.

Pathways

ApoB is integrated within the lipid metabolism pathway. It interacts with proteins such as microsomal triglyceride transfer protein (MTP) during the assembly and secretion of lipoproteins. This pathway is essential for the normal transport of lipids throughout the body and influences processes like absorption of dietary fats. ApoB also plays a role in the pathways related to atherosclerosis where it influences the deposition of cholesterol in arterial walls.

ApoB is well-associated with cardiovascular diseases notably atherosclerosis and familial hypercholesterolemia. In these conditions elevated levels of ApoB correlate to an increased risk of plaque formation in blood vessels. ApoB in conjunction with LDL receptor and other related proteins influences lipid homeostasis and disorders where lipid oxidation or accumulation is present. Monitoring ApoB and its concentration can be vital for assessing cardiovascular disease risk.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
See full target information APOB

대체 명칭 보기

Apolipoprotein B-100, Apo B-100, APOB, Apolipoprotein B100
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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of lipid research 61:455-463 PubMed31888979

2020

Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method.

Applications

Unspecified application

Species

Unspecified reactive species

Grace Marie Jones,Russell Caccavello,Sergiu P Palii,Clive R Pullinger,John P Kane,Kathleen Mulligan,Alejandro Gugliucci,Jean-Marc Schwarz

Redox report : communications in free radical rese 19:154-60 PubMed24524596

2014

Evidence for the presence of active paraoxonase 1 in small-dense low-density lipoprotein.

Applications

Unspecified application

Species

Unspecified reactive species

Alejandro Gugliucci,Russell Caccavello,Kazuhiko Kotani,Satoshi Kimura

Clinical biochemistry 47:475-7 PubMed24362269

2013

Small-dense low-density lipoproteins are the predominant apoB-100-containing lipoproteins in cord blood.

Applications

WB

Species

Human

Alejandro Gugliucci,Masahide Numaguchi,Russell Caccavello,Satoshi Kimura
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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