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AB122036

Anti-HSD17B13 antibody

4

(1 리뷰)

|

(3 제품이 사용된 논문 )

Rabbit Polyclonal HSD17B13 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human HSD17B13 aa 100-250.

대체 명칭 보기

SCDR9, SDR16C3, HMFN0376, UNQ497/PRO1014, HSD17B13, 17-beta-hydroxysteroid dehydrogenase 13, 17-beta-HSD 13, Hepatic retinol/retinal dehydrogenase, Short chain dehydrogenase/reductase family 16C member 3, Short-chain dehydrogenase/reductase 9

5 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)

Immunohistochemical analysis of human skin tissue labeling HSD17B13 with ab122036 at 1/200 dilution. Moderate granular cytoplasmic positivity in basal epidermal cells is shown.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)

Immunohistochemical analysis of human liver tissue labeling HSD17B13 with ab122036 at 1/200 dilution. Moderate to strong granular cytoplasmic positivity in hepatocytes is shown.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)

Immunohistochemical analysis of human placenta tissue labeling HSD17B13 with ab122036 at 1/500 dilution. As expected, no positivity in trophoblastic cells is shown.

Immunocytochemistry/ Immunofluorescence - Anti-HSD17B13 antibody (AB122036)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-HSD17B13 antibody (AB122036)

Immunofluorescent staining of Human cell line U-251MG shows positivity in golgi apparatus and vesicles. Recommended concentration of ab122036 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B13 antibody (AB122036)

Immunohistochemical analysis of human tonsil tissue labeling HSD17B13 with ab122036 at 1/200 dilution. As expected, no positivity in lymphoid cells is shown.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human HSD17B13 aa 100-250. The exact immunogen used to generate this antibody is proprietary information.

Q7Z5P4

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Plays a pivotal role in hepatic lipid metabolism (PubMed : 29562163). In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4 (PubMed : 29562163, PubMed : 30415504, PubMed : 32973038).. Isoform 2. Has retinol/retinal dehydrogenase activity in vitro.. Isoform 1. Does not have retinol/retinal dehydrogenase activity in vitro.
See full target information HSD17B13

제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The EMBO journal 43:6383-6409 PubMed39496977

2024

Rab2A-mediated Golgi-lipid droplet interactions support very-low-density lipoprotein secretion in hepatocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Min Xu,Zi-Yue Chen,Yang Li,Yue Li,Ge Guo,Rong-Zheng Dai,Na Ni,Jing Tao,Hong-Yu Wang,Qiao-Li Chen,Hua Wang,Hong Zhou,Yi-Ning Yang,Shuai Chen,Liang Chen

American journal of physiology. Endocrinology and metabolism 312:E357-E367 PubMed28270440

2017

Liver X receptor α induces 17β-hydroxysteroid dehydrogenase-13 expression through SREBP-1c.

Applications

Unspecified application

Species

Unspecified reactive species

Wen Su,Jun Peng,Sha Li,Yu-Bing Dai,Chun-Jiong Wang,Hu Xu,Min Gao,Xiong-Zhong Ruan,Jan-Åke Gustafsson,You-Fei Guan,Xiao-Yan Zhang

Proceedings of the National Academy of Sciences of the United States of America 111:11437-42 PubMed25028495

2014

Comparative proteomic study reveals 17β-HSD13 as a pathogenic protein in nonalcoholic fatty liver disease.

Applications

Unspecified application

Species

Human

Wen Su,Yang Wang,Xiao Jia,Wenhan Wu,Linghai Li,Xiaodong Tian,Sha Li,Chunjiong Wang,Huamin Xu,Jiaqi Cao,Qifei Han,Shimeng Xu,Yong Chen,Yanfeng Zhong,Xiaoyan Zhang,Pingsheng Liu,Jan-Åke Gustafsson,Youfei Guan
제품이 사용된 논문 모두 보기

Product promise

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