AB167417

Anti-HSD3B1 antibody [EPR9687]

20ul selling size
RabMAb
Recombinant
각 태그의 뜻

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(7 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal HSD3B1 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 7 publications.

2 이미지

Immunocytochemistry/ Immunofluorescence - Anti-HSD3B1 antibody [EPR9687] (AB167417)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-HSD3B1 antibody [EPR9687] (AB167417)

Immunofluorescent analysis of Caco-2 cells labeling HSD3B1 with ab167417 at 1/250 dilution.

Unknown

Western blot - Anti-HSD3B1 antibody [EPR9687] (AB167417)

All lanes:

Western blot - Anti-HSD3B1 antibody [EPR9687] (ab167417) at 1/1000 dilution

All lanes:

Human placenta cell lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP antibody at 1/2000 dilution

Predicted band size: 42 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR9687

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

The immunogen used for this product shares 83% homology and 6 continuous identical amino acids with HSD3B2(SwissProt: P26439). Cross-reactivity with this protein has not been confirmed experimentally.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/250 - 1/500", "ICCIF-species-notes": "" } } }

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제품 세부 정보

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형

Liquid

Purity

Tissue culture supernatant

보관 버퍼

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis. Specifically catalyzes the conversion of pregnenolone to progesterone, 17alpha-hydroxypregnenolone to 17alpha-hydroxyprogesterone, dehydroepiandrosterone (DHEA) to 4-androstenedione, and androstenediol to testosterone. Additionally, catalyzes the interconversion between 3beta-hydroxy and 3-oxo-5alpha-androstane steroids controlling the bioavalability of the active forms. Specifically converts dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR. Also converts androstanedione, a precursor of testosterone and estrone, to epiandrosterone (PubMed : 1401999, PubMed : 2139411). Expected to use NAD(+) as preferred electron donor for the 3beta-hydroxy-steroid dehydrogenase activity and NADPH for the 3-ketosteroid reductase activity (Probable).

See full target information HSD3B1

대체 명칭 보기

3BH, HSDB3A, HSD3B1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-Delta(5)-steroid dehydrogenase, 3-beta-hydroxysteroid 3-dehydrogenase, Delta-5-3-ketosteroid isomerase, Dihydrotestosterone oxidoreductase, Steroid Delta-isomerase, Trophoblast antigen FDO161G, 3-beta-HSD I

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제품이 사용된 논문 (7)

Recent publications for all applications. Explore the 전체 목록and refine your search

Zoological research 46:1108-1120 PubMed41017397

2025

CircSHOC2 regulates steroid hormone synthesis in ovarian granulosa cells through the mir-130b-5p/ASH1L pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Lu-Tong Zhang,Teng Zhang,Xiang-Rong Song,Madaniyati Mie-Lie,Yi-Hao Li,Lei Gao,Gong-She Yang,Gui-Yan Chu

Reproductive biomedicine online 50:104296 PubMed39626468

2024

Characteristics of polycystic ovary syndrome rat models induced by letrozole, testosterone propionate and high-fat diets.

Applications

Unspecified application

Species

Unspecified reactive species

Runan Hu,Yanjing Huang,Zhuo Liu,Haoxu Dong,Wenwen Ma,Kunkun Song,Xiaohu Xu,Xiao Wu,Yuli Geng,Fan Li,Mingmin Zhang,Yufan Song

International journal of molecular sciences 22: PubMed33445576

2021

Protease Inhibitor Anti-HIV, Lopinavir, Impairs Placental Endocrine Function.

Applications

Unspecified application

Species

Unspecified reactive species

Camille Fraichard,Fidéline Bonnet-Serrano,Christelle Laguillier-Morizot,Marylise Hebert-Schuster,René Lai-Kuen,Jeanne Sibiude,Thierry Fournier,Marie Cohen,Jean Guibourdenche

Nanomaterials (Basel, Switzerland) 10: PubMed32635405

2020

Uptake of Cerium Dioxide Nanoparticles and Impact on Viability, Differentiation and Functions of Primary Trophoblast Cells from Human Placenta.

Applications

Unspecified application

Species

Unspecified reactive species

Margaux Nedder,Sonja Boland,Stéphanie Devineau,Amal Zerrad-Saadi,Jasmina Rogozarski,René Lai-Kuen,Ibtissem Baya,Jean Guibourdenche,Francoise Vibert,Audrey Chissey,Sophie Gil,Xavier Coumoul,Thierry Fournier,Ioana Ferecatu

Journal of applied toxicology : JAT 40:947-964 PubMed32072669

2020

Effects of isolated or combined exposure to sibutramine and rosuvastatin on reproductive parameters of adult male rats.

Applications

Unspecified application

Species

Unspecified reactive species

Patrícia Villela E Silva,Cibele Dos Santos Borges,Josiane de Lima Rosa,Tainá Louise Pacheco,Thamiris Moreira Figueiredo,Gabriel Adan Araújo Leite,Marina Trevizan Guerra,Janete Aparecida Anselmo-Franci,Gary Robert Klinefelter,Wilma De Grava Kempinas

Molecular and cellular endocrinology 499:110586 PubMed31539598

2019

Placental production of progestins is fully effective in villous cytotrophoblasts and increases with the syncytiotrophoblast formation.

Applications

Unspecified application

Species

Unspecified reactive species

C Fraichard,F Bonnet,A Garnier,M Hébert-Schuster,A Bouzerara,P Gerbaud,I Ferecatu,T Fournier,I Hernandez,S Trabado,J Guibourdenche

Molecular and cellular biology 39: PubMed30988160

2019

Growth Factor Independence 1B-Mediated Transcriptional Repression and Lineage Allocation Require Lysine-Specific Demethylase 1-Dependent Recruitment of the BHC Complex.

Applications

Unspecified application

Species

Unspecified reactive species

David McClellan,Mattie J Casey,Diana Bareyan,Helena Lucente,Christopher Ours,Matthew Velinder,Jason Singer,Mehraju Din Lone,Wenxiang Sun,Yunuen Coria,Clinton C Mason,Michael E Engel

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-HSD3B1 antibody [EPR9687]

Immunocytochemistry/ Immunofluorescence - Anti-HSD3B1 antibody [EPR9687] (AB167417)

Western blot - Anti-HSD3B1 antibody [EPR9687] (AB167417)

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

대체품

Primary Antibodies

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

Purity

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (7)

Product promise