AB2213

Anti-ICAM1 antibody [MEM-111]

Name: Anti-ICAM1 항체 [MEM-111] (ab2213) | Abcam
Brand: Abcam Limited
SKU: AB2213
Rating: 4 (12 reviews)

Anti-ICAM1 항체 [MEM-111]

(12 리뷰들)

(95 제품이 사용된 논문 )

Mouse Monoclonal ICAM1 antibody. Suitable for WB, Flow Cyt and reacts with Human samples. Cited in 95 publications. Immunogen corresponding to Cell preparation containing ICAM1 protein.

대체 명칭 보기

CD54, Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, ICAM1

2 이미지

Flow Cytometry - Anti-ICAM1 antibody [MEM-111] (AB2213)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-ICAM1 antibody [MEM-111] (AB2213)

Flow cytometric analysis of Human Peripheral Blood cells labelling ICAM1 with ab2213 at 0.6 ug/ml showing separation of human monocytes (red-filled) from human lymphocytes (black-dashed).

Supplier Data

Western blot - Anti-ICAM1 antibody [MEM-111] (AB2213)

Lower bands represent tubulin as a loading control.

All lanes:

Western blot - Anti-ICAM1 antibody [MEM-111] (ab2213)

Lane 1:

TNF-alpha activated HUVEC (Human umbilical vein endothelial cell line) whole cell lysate

Lane 2:

TNF-alpha nonactivated HUVEC cells

Predicted band size: 57 kDa

Observed band size: 90 kDa

false

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-111

Isotype

IgG2a

Light chain 타입

unknown

Carrier free

Reacts with

Human

Applications

Flow Cyt, WB

applications

Immunogen

Cell preparation containing ICAM1 protein. The exact immunogen used to generate this antibody is proprietary information.

P05362

Specificity

his antibody reacts with human CD54 antigen.

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대체품

Primary Antibodies

AB179707

Anti-ICAM1 antibody [EPR16608]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry - Anti-ICAM1 antibody [EPR16608] (AB179707)

Primary Antibodies

AB53013

Anti-ICAM1 antibody [EP1442Y]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAM1 antibody [EP1442Y] (AB53013)

Primary Antibodies

AB221777

Anti-ICAM1 antibody [EP1442Y] - Low endotoxin, Azide free

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAM1 antibody [EP1442Y] - Low endotoxin, Azide free (AB221777)

Primary Antibodies

AB109361

Anti-ICAM1 antibody [EPR4776]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-ICAM1 antibody [EPR4776] (AB109361)

Primary Antibodies

AB222736

Anti-ICAM1 antibody [EPR22161-284]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAM1 antibody [EPR22161-284] (AB222736)

Primary Antibodies

AB206398

Anti-ICAM1 antibody [EPR19938]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAM1 antibody [EPR19938] (AB206398)

보완 제품

Assay Kits

AB174445

Human ICAM1 ELISA Kit (CD54)

SimpleStep

ELISA - Human ICAM1 ELISA Kit (CD54) (AB174445)

Primary Antibodies

AB134047

Anti-VCAM1 antibody [EPR5047]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|KO Validated

Western blot - Anti-VCAM1 antibody [EPR5047] (AB134047)

Primary Antibodies

AB24982

Cy5 ® Anti-CD45.1 antibody [A20]

Primary Antibodies

AB178846

Anti-Iba1 antibody [EPR16588] - Microglia marker

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Iba1 antibody [EPR16588] - Microglia marker (AB178846)

Primary Antibodies

AB9498

Anti-CD31 antibody [JC/70A]

BOND RX™ Validated|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody [JC/70A] (AB9498)

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p>Use under non-reducing conditions.</p>", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.5-4 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL : ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing a calibrated system to namely adjust T-cell killing to the antigen stimulation strength (PubMed : 3086451, PubMed : 3340213, PubMed : 38195629). Also functions as a ligand receptor of the signaling receptor ITGAM : ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed : 1980124). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (PubMed : 17875742). Promotes cell aggregation in epithelial cells through interaction with MUC1 (PubMed : 11173916).. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins.. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins.. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.

See full target information ICAM1

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제품이 사용된 논문 (95)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Biomaterials science 13:6368-6377 PubMed41044926

2025

A tissue-engineered endothelial cell - smooth muscle cell arteriole-like model.

Applications

Unspecified application

Species

Unspecified reactive species

Ninghao Zhu,Lily Liang,Nan Zhao,Haosong Chen,Peter C Searson

Diabetology & metabolic syndrome 17:328 PubMed40804414

2025

Mechanisms and clinical translation of ICOS/ICOSL signaling pathway blockade in delaying vascular complications of type 2 diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Haiyan Zhang,LiBo Ruan,Xuemei Fu,Jinwen Yu,Qingrong Ruan,Yiyu Li,Hongying Wang,Heng Shao,Haoran Dong,Jianglan Cui

Frontiers in pharmacology 16:1579551 PubMed40520162

2025

Respiratory virus-induced bacterial dysregulation in pediatric airway tissue and the dual actions of Echinacea in reducing complications.

Applications

Unspecified application

Species

Unspecified reactive species

Selvarani Vimalanathan,Mahfuza Sreya,Ranganayaki Nandanavanam,Roland Schoop,Giuseppe Gancitano,Saba Saberi,Anna Malikovskaia,James Hudson

APL bioengineering 9:026122 PubMed40510858

2025

Pulsatile low shear stress increases susceptibility to endothelial inflammation via upregulation of IFT and activation of YAP.

Applications

Unspecified application

Species

Unspecified reactive species

Yu Hou,Hazel R C Screen,Martin M Knight

Inflammation 48:2531-2547 PubMed39739157

2025

Sustained Vascular Inflammatory Effects of SARS-CoV-2 Spike Protein on Human Endothelial Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Mitra Gultom,Lin Lin,Camilla Blunk Brandt,Anastasia Milusev,Alain Despont,Jane Shaw,Yvonne Döring,Yonglun Luo,Robert Rieben

Frontiers in immunology 15:1452788 PubMed39493750

2024

Circulating IL-17F, but not IL-17A, is elevated in severe COVID-19 and leads to an ERK1/2 and p38 MAPK-dependent increase in ICAM-1 cell surface expression and neutrophil adhesion on endothelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Jérôme Bédard-Matteau,Antoine Soulé,Katelyn Yixiu Liu,Lyvia Fourcade,Douglas D Fraser,Amin Emad,Simon Rousseau

Cell death & disease 15:605 PubMed39168965

2024

Neoplastic ICAM-1 protects lung carcinoma from apoptosis through ligation of fibrinogen.

Applications

Unspecified application

Species

Unspecified reactive species

ShiHui Wang,JunLei Wang,Cui Liu,Lei Yang,XuanQian Tan,ShiYang Chen,Yun Xue,HongBin Ji,GaoXiang Ge,JianFeng Chen

Heliyon 10:e33932 PubMed39050471

2024

Tumor microenvironment (Part I): Tissue integrity in a rat model of peripheral neural cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ahmad Maqboul,Bakheet Elsadek

European journal of clinical investigation 54:e14212 PubMed38591651

2024

Elevated circulating BMP9 aggravates pulmonary angiogenesis in hepatopulmonary syndrome rats through ALK1-Endoglin-Smad1/5/9 signalling.

Applications

Unspecified application

Species

Unspecified reactive species

Chunyong Yang,Mei Sun,Yihui Yang,Yan Han,Xiulin Wu,Xianfeng Wu,Huilin Cao,Lin Chen,Yuhao Lei,Xiaoyan Hu,Yang Chen,Ziyang Zeng,Junhong Li,Xin Shu,Zhiyong Yang,Kaizhi Lu,Yujie Li,Xiaobo Wang,Bin Yi

Fluids and barriers of the CNS 20:80 PubMed37924145

2023

A tissue-engineered model of the blood-tumor barrier during metastatic breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Raleigh M Linville,Joanna Maressa,Zhaobin Guo,Tracy D Chung,Alanna Farrell,Ria Jha,Peter C Searson

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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