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AB317413

Anti-IFRD1 antibody [S05-2H2]

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Rabbit Recombinant Monoclonal IFRD1 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human IFRD1.

대체 명칭 보기

Interferon-related developmental regulator 1, Nerve growth factor-inducible protein PC4, IFRD1

1 이미지
Western blot - Anti-IFRD1 Antibody [S05-2H2] (AB317413)
  • WB

Supplier Data

Western blot - Anti-IFRD1 Antibody [S05-2H2] (AB317413)

All lanes:

Western blot - Anti-IFRD1 Antibody [S05-2H2] (ab317413) at 1/1000 dilution

All lanes:

Ramos cell lysate

Predicted band size: 50 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

S05-2H2

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human IFRD1.

O00458

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보완 제품

Primary Antibodies

AB16895

Anti-MDM2 antibody [2A10]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MDM2 antibody [2A10] (AB16895)

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Primary Antibodies

AB79352

Anti-RPL11 antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL11 antibody (AB79352)

  • 4
  • 3
Primary Antibodies

AB183734

Anti-GFP antibody [EPR14104]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [EPR14104] (AB183734)

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Primary Antibodies

AB86863

Anti-RPL5 antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPL5 antibody (AB86863)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" } } }
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제품 세부 정보

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
pH: 7.4 Preservative: 0.01% Sodium azide Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Interferon-related developmental regulator 1 (IFRD1) also known as PC4 is involved in transcription regulation and cellular differentiation. It is a nuclear protein with a mass of approximately 48 kDa. IFRD1 is expressed in various tissue types including muscle lung and the immune system among others. As a transcriptional co-regulator it modulates the activity of several transcription factors through interactions with other proteins affecting gene expression patterns.
Biological function summary

IFRD1 regulates immune response and cellular differentiation processes. It functions as part of the transcriptional regulation complex influencing genes involved in tissue regeneration and repair. In the immune system IFRD1 modulates macrophage activation and influences neutrophil survival. The involvement in these biological processes indicates its important role in both normal physiological functions and response to injury or inflammation.

Pathways

IFRD1 significantly contributes to the NF-kB signaling and JAK/STAT pathways. In these pathways it interacts with key regulatory proteins to influence transcriptional outcomes. The NF-kB pathway for instance involves interactions with transcription factors that control inflammation and immune responses. Meanwhile the JAK/STAT pathway important for cytokine signaling sees IFRD1 engaging with STAT proteins. Through these pathways IFRD1 plays a role in regulating cellular responses to external stimuli.

IFRD1 associates with cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). Research links IFRD1 with modulation of inflammation where improper regulation can exacerbate respiratory conditions as observed in CF. In COPD impaired IFRD1 function may lead to increased inflammation and deteriorated lung function. Relationships with other proteins such as the CFTR gene product in cystic fibrosis highlight IFRD1's potential role in the pathophysiology of these diseases offering insights into possible therapeutic interventions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).
See full target information IFRD1
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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