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AB313421

Anti-IGF2BP2/IMP-2 antibody [RP23040258]

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Rabbit Recombinant Multiclonal IGF2BP2/IMP-2 antibody. Suitable for ICC/IF, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human IGF2BP2.

대체 명칭 보기

IMP2, VICKZ2, IGF2BP2, Insulin-like growth factor 2 mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, VICKZ family member 2

1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-IGF2BP2/IMP-2 Antibody [RP23040258] (AB313421)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-IGF2BP2/IMP-2 Antibody [RP23040258] (AB313421)

Immunofluorescent analysis of Hep G2 cells fixed with 4% formaldehyde reconstituted in 1X PBS for 10 min at room temperature and permeabilized with 0.1 % Triton X-100 in PBS for 15 min at room temperature labeling endogenous IGF2BP2/IMP-2 with ab313421 at 1/100 dilution followed by Goat anti-Rabbit IgG (H+L) Secondary Antibody, Alexa Fluor® 488 conjugate at 1/2000 dilution. Nuclei (blue) were stained using DAPI, and Rhodamine Phalloidin at 1/300 dilution was used for cytoskeletal F-actin (red) staining. Panel a-d) clearly demonstrates cytoplasmic localization of IGF2BP2/IMP-2 in Hep G2 cells. Panel e-h) shows no specific staining in MCF7 cells which is IGF2BP2/IMP-2 negative, demonstrating specificity. The images were captured at 60X magnification.

주요 정보

Host species

Rabbit

Clonality

Multiclonal

Clone number

RP23040258

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF

applications

Immunogen

Synthetic Peptide within Human IGF2BP2. Database link Q9Y6M1

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보완 제품

Primary Antibodies

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Anti-METTL3 antibody [EPR18810]

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Immunohistochemistry - Anti-METTL3 antibody [EPR18810] (AB195352)

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Primary Antibodies

AB177477

Anti-IMP3 antibody [EPR12021]

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Flow Cytometry (Intracellular) - Anti-IMP3 antibody [EPR12021] (AB177477)

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Primary Antibodies

AB184305

Anti-IGF2BP1/IMP1 antibody [EPR18791]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IGF2BP1/IMP1 antibody [EPR18791] (AB184305)

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  • 0
Primary Antibodies

AB220163

Anti-YTHDF2 antibody [EPR20318]

20ul selling size|RabMAb|Recombinant|KO Validated

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  • 5
  • 3
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100", "ICCIF-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" } } }
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제품 세부 정보

What are recombinant multiclonals?
Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains. They offer several advantages including:

  • - The sensitivity of polyclonal antibodies by recognising multiple epitopes
  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

View our range of recombinant multiclonal antibodies.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Preferentially binds to N6-methyladenosine (m6A)-containing mRNAs and increases their stability (PubMed : 29476152). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs (PubMed : 9891060). Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts. Increases MYC mRNA stability by binding to the coding region instability determinant (CRD) and binding is enhanced by m6A-modification of the CRD (PubMed : 29476152).
See full target information IGF2BP2
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of nanobiotechnology 22:298 PubMed38811968

2024

Exosome-derived circUPF2 enhances resistance to targeted therapy by redeploying ferroptosis sensitivity in hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Feng-Lin Dong,Zong-Zhen Xu,Ying-Qiao Wang,Tao Li,Xin Wang,Jie Li
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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