JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB233754

Anti-IL-28A antibody [6H9E6]

Be the first to review this product! 리뷰 제출

|

(2 제품이 사용된 논문 )

Mouse Monoclonal IFNL2 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IFNL2.

대체 명칭 보기

IL28A, ZCYTO20, IFNL2, Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A

3 이미지
Immunocytochemistry/ Immunofluorescence - Anti-IL-28A antibody [6H9E6] (AB233754)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-IL-28A antibody [6H9E6] (AB233754)

HeLa (human prostate adenocarcinoma cell line) cells stained for IL28A (green) using ab233754 at 1/200 dilution in ICC/IF.

Blue : DRAQ5 fluorescent DNA dye. Red : Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Western blot - Anti-IL-28A antibody [6H9E6] (AB233754)
  • WB

Supplier Data

Western blot - Anti-IL-28A antibody [6H9E6] (AB233754)

Expected MW is 48.2 kDa.

All lanes:

Western blot - Anti-IL-28A antibody [6H9E6] (ab233754) at 1/500 dilution

All lanes:

Human IL28A (aa 1-200) recombinant protein

Predicted band size: 22 kDa,28 kDa

false

Western blot - Anti-IL-28A antibody [6H9E6] (AB233754)
  • WB

Supplier Data

Western blot - Anti-IL-28A antibody [6H9E6] (AB233754)

Lanes 1 - 2:

Western blot - Anti-IL-28A antibody [6H9E6] (ab233754) at 1/500 dilution

Lanes 1 - 2:

Western blot - Anti-AIM2 antibody [7G12D1] (<a href='/ko/products/primary-antibodies/aim2-antibody-7g12d1-ab233756'>ab233756</a>) at 1/500 dilution

Lane 1:

HEK-293 (human epithelial cell line from embryonic kidney) whole cell lysate

Lane 2:

IL28A (aa 1-200)-hIgGFc transfected HEK-293 cell lysate

Predicted band size: 22 kDa,39 kDa

true

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

6H9E6

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human IFNL2.

Q8IZJ0

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/200 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purified from tissue culture supernatant.
보관 버퍼
Preservative: 0.05% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets : is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
See full target information IFNL2

제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of molecular medicine 52: PubMed37449511

2023

E74‑like ETS transcription factor 5 facilitates cell proliferation through regulating the expression of adenomatous polyposis coli 2 in non‑small cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Wen,Genggeng Qin,Zhaojing Jiang,Zixun Lin,Ruixin Zhou,Hui Dai,Zhanfa Xu,Weiguo Chen,Qiancheng Song

International journal of molecular sciences 23: PubMed35806255

2022

Targeted Modulation of Interferon Response-Related Genes with IFN-Alpha/Lambda Inhibition.

Applications

Unspecified application

Species

Unspecified reactive species

Debpali Sur,Katerina Leonova,Bar Levi,Shany Ivon Markowitz,Raichel Cohen-Harazi,Ilya Gitlin,Katerina Gurova,Andrei Gudkov,Albert Pinhasov,Igor Koman,Elimelech Nesher
제품이 사용된 논문 모두 보기

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com