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AB75061

Anti-INSL4 antibody

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Rabbit Polyclonal INSL4 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human Early placenta insulin-like peptide.
2 이미지
Immunocytochemistry/ Immunofluorescence - Anti-INSL4 antibody (AB75061)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-INSL4 antibody (AB75061)

ab75061, at 1/500 dilution, staining of A549 cells using Immunofluorescence analysis.
1) Without immunising peptide
2) With immunising peptide

Western blot - Anti-INSL4 antibody (AB75061)
  • WB

Unknown

Western blot - Anti-INSL4 antibody (AB75061)

All lanes:

Western blot - Anti-INSL4 antibody (ab75061) at 1/500 dilution

Lane 1:

extracts from HT-29 cells at 5 µg

Lane 2:

extracts from HT-29 cells at 5 µg with immunising peptide

Predicted band size: 15 kDa

Observed band size: 19 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Human Early placenta insulin-like peptide. The exact immunogen used to generate this antibody is proprietary information.

Q14641

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보완 제품

Primary Antibodies

AB314134

Anti-Claudin 6 antibody [EPR28103-113]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Claudin 6 antibody [EPR28103-113] (AB314134)

  • 0
  • 0
Assay Kits

AB320044

Human Stanniocalcin 2 / STC-2 ELISA Kit- Extracellular

Recombinant|SimpleStep

Sandwich ELISA - Human Stanniocalcin 2 / STC-2 ELISA Kit- Extracellular (AB320044)

  • 0
  • 0
Primary Antibodies

AB219971

Anti-KK-LC-1 antibody [CL4762]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KK-LC-1 antibody [CL4762] (AB219971)

  • 0
  • 0
Primary Antibodies

AB245019

Anti-PRAME antibody [EPR20366-80] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-PRAME antibody [EPR20366-80] - BSA and Azide free (Detector) (AB245019)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/500 - 1/1000", "ICCIF-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
ab75061 was purified using an epitope-specific immunogen.
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

INSL4 also known as insulin-like 4 is a protein with a mass of approximately 15.8 kDa. This protein originates within the insulin superfamily and functions mechanically by playing a role in cell signaling. INSL4 exhibits expression mainly in placenta-related tissues suggesting its involvement in pregnancy-related processes. It differs from other insulin-like peptides in terms of both its sequence and specific roles in reproduction.
Biological function summary

INSL4 takes part in regulating placental development and can influence trophoblast differentiation. This protein operates independently rather than as a component of larger protein complexes. In early pregnancy INSL4 contributes to fetal tissue formation and influences cellular growth and differentiation. This makes INSL4 an important marker and functional molecule in embryonic development contexts.

Pathways

INSL4 joins several critical signaling cascades related to cell growth and differentiation. The protein is a participant in the insulin signaling pathway and can interact with receptors similar to those recognized by insulin and insulin-like growth factors. Additionally INSL4 connects with IGF1 and IGF2 in these pathways highlighting its role in tissue development and metabolic regulation.

INSL4 links to conditions such as pregnancy-related trophoblastic disease and certain types of cancer. Its aberrant expression or function may lead to complications during pregnancy or contribute to the progression of malignant cells. In trophoblastic diseases INSL4 might interact with proteins like hCG while in cancer connections with oncogenes such as ERK or PI3K signaling components might occur. Understanding these associations can shed light on potential biomarker or therapeutic roles for INSL4 in clinical settings.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May play an important role in trophoblast development and in the regulation of bone formation.
See full target information Early placenta insulin-like peptide

대체 명칭 보기

Early placenta insulin-like peptide, EPIL, Insulin-like peptide 4, Placentin, INSL4
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Genetics, selection, evolution : GSE 57:23 PubMed40394457

2025

A bovine model of rhizomelic chondrodysplasia punctata caused by a deep intronic splicing variant in the GNPAT gene.

Applications

Unspecified application

Species

Unspecified reactive species

Arnaud Boulling,Julien Corbeau,Cécile Grohs,Anne Barbat,Jérémy Mortier,Sébastien Taussat,Vincent Plassard,Hélène Leclerc,Sébastien Fritz,Cyril Leymarie,Lorraine Bourgeois-Brunel,Alain Ducos,Raphaël Guatteo,Didier Boichard,Mekki Boussaha,Aurélien Capitan
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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