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AB235372

Anti-IPT antibody

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Rabbit Polyclonal IPT antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TRIT1.

대체 명칭 보기

IPT, MOD5, TRIT1, tRNA dimethylallyltransferase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, hGRO1, tRNA isopentenyltransferase 1, IPP transferase, IPPT, IPTase

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Full Length Protein corresponding to Human TRIT1.

Q9H3H1

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The biological target 'IPT' also known as isopentenyl transferase is an enzyme involved in the catalysis of certain biochemical reactions. This enzyme has a molecular mass of approximately 32 kDa and is often expressed in various plant tissues including roots shoots and leaves. In the context of its role IPT facilitates the transfer of the isopentenyl group to adenine leading to the biosynthesis of cytokinins which are essential hormones for plant growth and development.
Biological function summary

IPT plays a central role in cytokinin biosynthesis by converting dimethylallyl diphosphate (DMAPP) and adenosine monophosphate (AMP) into isopentenyl adenine a precursor of cytokinin. Cytokinins together with auxins regulate cell division differentiation and apical dominance. IPT is often found as a part of a complex network of enzymatic reactions contributing to these processes. Its activity profoundly affects plant morphology and physiology by influencing the allocation of resources and determining plant architecture.

Pathways

IPT fits into the cytokinin biosynthetic pathway collaborating with other enzymes involved in plant hormone regulation. It plays an important role in modulating the balance between cytokinin and auxin levels which controls many developmental processes. The enzyme is closely associated with the IPT family of proteins and interfaces with the homodomain transcription factors that regulate plant growth responses to environmental stimuli. This places IPT in pivotal intersection points of hormonal and stress response pathways in plants.

Research highlights the importance of IPT's manipulation in plant biotechnology for crop improvement and stress resistance. Its association with increased cytokinin production has shown benefits such as delayed leaf senescence and enhanced resistance to drought and pathogens. There are indirect links between IPT and proteins involved in disease resistance pathways such as the pathogenesis-related proteins. Exploiting IPT's function in agricultural settings can lead to better yield stability and reduced agricultural losses due to environmental stressors.

제품 프로토콜

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타겟 정보

Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 of both cytosolic and mitochondrial tRNAs, leading to the formation of N6-(dimethylallyl)adenosine (i6A37) (PubMed : 11111046, PubMed : 24126054, PubMed : 24901367, PubMed : 34774131). Mediates modification of a limited subset of tRNAs : tRNA(Ser)(AGA), tRNA(Ser)(CGA), tRNA(Ser)(UGA), as well as partial modification of the selenocysteine tRNA(Ser)(UCA) (PubMed : 24126054). TRIT1 is therefore required for selenoprotein expression (PubMed : 24126054).
See full target information TRIT1

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Science advances 10:eado3141 PubMed39047111

2024

Atf3-mediated metabolic reprogramming in hepatic macrophage orchestrates metabolic dysfunction-associated steatohepatitis.

Applications

Unspecified application

Species

Unspecified reactive species

Shuwei Hu,Rui Li,Dongxu Gong,Pei Hu,Jitu Xu,Yingjie Ai,Xiaojie Zhao,Chencheng Hu,Minghuan Xu,Chenxi Liu,Shuyu Chen,Jie Fan,Zhonghua Zhao,Zhigang Zhang,Huijuan Wu,Yanyong Xu
제품이 사용된 논문 모두 보기

Product promise

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