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AB114997

Anti-IRF2BP2 antibody

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(1 출판물)

Rabbit Polyclonal IRF2BP2 antibody. Suitable for IP and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human IRF2BP2 aa 200 to C-terminus.

대체 명칭 보기

Interferon regulatory factor 2-binding protein 2, IRF-2-binding protein 2, IRF-2BP2, IRF2BP2

1 이미지
Immunoprecipitation - Anti-IRF2BP2 antibody (AB114997)
  • IP

Unknown

Immunoprecipitation - Anti-IRF2BP2 antibody (AB114997)

Immunoprecipitation : 1 mg of HeLa cell lysate immunoprecipitated using ab114997 at 6 µg/mg lysate; 20% of immunoprecipitate was loaded/lane.
Western Blot of immunoprecipitate : Anti-IRF2BP2 antibody at 1 µg/ml.
Developed using the ECL technique
Exposure time : 1 second
Predicted band size : 61 kDa

All lanes:

Immunoprecipitation - Anti-IRF2BP2 antibody (ab114997)

Predicted band size: 54 kDa,61 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP

applications

Immunogen

Synthetic Peptide within Human IRF2BP2 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q7Z5L9

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대체품

Primary Antibodies

AB124163

Anti-IRF2BP2 antibody

Western blot - Anti-IRF2BP2 antibody (AB124163)

  • 3
  • 4
Primary Antibodies

AB217361

Anti-IRF2BP2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IRF2BP2 antibody (AB217361)

  • 0
  • 0

보완 제품

Assay Kits

AB197010

MTS Assay Kit (Cell Proliferation) (Colorimetric)

Biochemical assay - MTS Assay Kit (Cell Proliferation) (Colorimetric) (AB197010)

  • 0
  • 0
Primary Antibodies

AB178846

Anti-Iba1 antibody [EPR16588] - Microglia marker

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Iba1 antibody [EPR16588] - Microglia marker (AB178846)

  • 5
  • 50
Primary Antibodies

AB313900

Alexa Fluor® 488 Anti-CD11c antibody [KB90]

Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 488 Anti-CD11c antibody [KB90] (AB313900)

  • 0
  • 0
Primary Antibodies

AB24982

Cy5 ® Anti-CD45.1 antibody [A20]

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "<p></p>" }, "Chimpanzee": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" }, "Rhesus monkey": { "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
ab114997 was affinity purified using an epitope specific to IRF2BP2 immobilized on solid support.
보관 버퍼
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The IRF2BP2 also known as Interferon Regulatory Factor 2 Binding Protein 2 has a mass of approximately 68 kDa. This protein acts mechanically as a transcriptional coregulator. It is involved in the regulation of gene expression by modulating the activity of the transcription factor IRF2. IRF2BP2 is found to be expressed in multiple tissues including the heart spleen and thymus which indicates its broad physiological significance.
Biological function summary

Acting as a transcriptional coregulator IRF2BP2 influences immune response cell differentiation and apoptosis. It functions in conjunction with other cellular components and may form complexes with proteins such as IRF2 and other transcription factors. The protein plays an important role in controlling immune function by either enhancing or suppressing gene expression in response to cellular stimuli.

Pathways

IRF2BP2 involves itself in the immune signaling pathways such as the NF-kB signaling. It also connects to the MAPK signaling pathway which is critical for cellular responses to stress and cytokines. It works closely with proteins such as NF-kB and IRF2 which are significant to these pathways and influence the transcription of target genes.

IRF2BP2 associates with cardiovascular disease and certain inflammatory conditions. In cardiovascular disease this protein may affect heart-related genes mainly through its interaction with IRF2 and possibly through the modulation of inflammatory responses. In inflammatory disorders IRF2BP2 has a regulatory function which involves NF-kB to control excessive inflammatory gene expression influencing disease progression.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities (PubMed : 12799427). Represses the NFAT1-dependent transactivation of NFAT-responsive promoters (PubMed : 21576369). Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles (PubMed : 20702774). Plays a role in immature B-cell differentiation (PubMed : 27016798).
See full target information IRF2BP2
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Animal cells and systems 25:264-271 PubMed34745433

2021

Prokinetic effects of diatrizoate meglumine (Gastrografin®) in a zebrafish for opioid-induced constipation model.

Applications

Unspecified application

Species

Unspecified reactive species

Dongwoo Kim,Soonil Koun,Seung Young Kim,Young Ran Ha,Jung Wan Choe,Sung Woo Jung,Jong Jin Hyun,Young Kul Jung,Ja Seol Koo,Hyung Joon Yim,Sang Woo Lee
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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