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AB235356

Anti-KRT35 antibody

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Rabbit Polyclonal KRT35 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human KRT35.

대체 명칭 보기

HHA5, HKA5, KRTHA5, KRT35, Keratin-35, K35

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KRT35 antibody (AB235356)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KRT35 antibody (AB235356)

Paraffin-embedded human prostate cancer tissue stained for KRT35 using ab235356 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KRT35 antibody (AB235356)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KRT35 antibody (AB235356)

Paraffin-embedded human skin tissue stained for KRT35 using ab235356 at 1/100 dilution in immunohistochemical analysis.

Western blot - Anti-KRT35 antibody (AB235356)
  • WB

Supplier Data

Western blot - Anti-KRT35 antibody (AB235356)

All lanes:

Western blot - Anti-KRT35 antibody (ab235356) at 1/500 dilution

All lanes:

PC-3 (human prostate adenocarcinoma cell line) whole cell lysate

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/10000 dilution

Predicted band size: 50 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human KRT35.

Q92764

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보완 제품

Primary Antibodies

AB58755

Anti-Trichohyalin antibody [AE15]

Western blot - Anti-Trichohyalin antibody [AE15] (AB58755)

  • 5
  • 2
Primary Antibodies

AB119695

Anti-Cytokeratin 14 antibody [SP53]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Cytokeratin 14 antibody [SP53] (AB119695)

  • 5
  • 6
Primary Antibodies

AB52816

Anti-Cytokeratin 15 antibody [EPR1614Y]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-Cytokeratin 15 antibody [EPR1614Y] (AB52816)

  • 5
  • 2
Primary Antibodies

AB76318

Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker

20ul selling size|RabMAb|Recombinant|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker (AB76318)

  • 5
  • 14
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

KRT35 also known as Keratin 35 is a type I keratin protein. As a structural protein with a mass of around 44 kDa KRT35 is primarily found in the hair shaft cortex where it aids in maintaining the integrity of hair. The protein belongs to the broader keratin family which includes many other keratins classified by acidic or basic nature. KRT35 is expressed mainly in hair follicle cells and relates to the cytoskeleton serving as an important component that supports cellular structure.
Biological function summary

KRT35 contributes to the mechanical stability and resilience of hair by forming intermediate filaments which are part of the hair's structural matrix. The protein interacts within a complex network of type I and type II keratins enabling a robust structural framework necessary for healthy hair development. KRT35's role in hair morphology is especially significant during hair follicle formation and cycling contributing to the keratinization process that forms the hair shaft.

Pathways

KRT35 operates within the keratinization and epithelial cell differentiation pathways. It closely interacts with other type I and II keratin proteins like KRT85 and KRT86 creating a network that influences hair and epidermal tissue formation. Understanding these interactions helps interpret how KRT35 is involved in complex biological systems and how it maintains the structure of epithelial cells.

Malfunction or mutations of KRT35 associate with hair shaft disorders such as monilethrix an autosomal dominant condition causing fragile hair. It shows connection with other keratin proteins like KRT86 where mutations can similarly lead to defects in hair structure. Additionally changes in KRT35 expression can affect hair growth and quality emphasizing its importance in maintaining healthy hair phenotype.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information KRT35
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of clinical endocrinology and metabolism 107:3328-3340 PubMed36074910

2022

Premature Ovarian Insufficiency in CLPB Deficiency: Transcriptomic, Proteomic and Phenotypic Insights.

Applications

Unspecified application

Species

Unspecified reactive species

Elena J Tucker,Megan J Baker,Daniella H Hock,Julia T Warren,Sylvie Jaillard,Katrina M Bell,Rajini Sreenivasan,Shabnam Bakhshalizadeh,Chloe A Hanna,Nikeisha J Caruana,Saskia B Wortmann,Shamima Rahman,Robert D S Pitceathly,Jean Donadieu,Aurelia Alimi,Vincent Launay,Paul Coppo,Sophie Christin-Maitre,Gorjana Robevska,Jocelyn van den Bergen,Brianna L Kline,Katie L Ayers,Phoebe N Stewart,David A Stroud,Diana Stojanovski,Andrew H Sinclair
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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