AB327111

Anti-LAMB1 Antibody [CL2970]

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Mouse Monoclonal LAMB1 antibody. Suitable for WB, IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human LAMB1.

대체 명칭 보기

Laminin subunit beta-1, Laminin B1 chain, Laminin-1 subunit beta, Laminin-10 subunit beta, Laminin-12 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-8 subunit beta, LAMB1

7 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LAMB1 Antibody [CL2970] (AB327111)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LAMB1 Antibody [CL2970] (AB327111)

Immunohistochemical staining of human endometrium using ab327111 at 1 : 50–1 : 200 dilution, showing immunoreactivity in basement membrane of glandular epithelium.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LAMB1 Antibody [CL2970] (AB327111)

Immunohistochemical staining of human placenta using ab327111 at 1 : 50–1 : 200 dilution, showing moderate immunoreactivity in basement membrane of trophoblast and in endothelium.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LAMB1 Antibody [CL2970] (AB327111)

Immunohistochemical staining of human pancreas using ab327111 at 1 : 50–1 : 200 dilution, showing moderate positivity in basement membrane of exocrine glands.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LAMB1 Antibody [CL2970] (AB327111)

Immunohistochemical staining of human stomach using ab327111 at 1 : 50–1 : 200 dilution, showing positivity in basement membrane of glandular epithelium.

Supplier Data

Western blot - Anti-LAMB1 Antibody [CL2970] (AB327111)

Western blot analysis in human placenta tissue using ab327111 at 1 µg/ml.

All lanes:

Western blot - Anti-LAMB1 Antibody [CL2970] (ab327111)

All lanes:

Human placenta tissue

Predicted band size: 198.04 kDa

false

Supplier Data

Western blot - Anti-LAMB1 Antibody [CL2970] (AB327111)

Western blot analysis of purified human recombinant Laminin-111, Laminin-211, Laminin-411, Laminin-511, Laminin-521 and Laminin-332 using ab327111 at 1 µg/ml.

All lanes:

Western blot - Anti-LAMB1 Antibody [CL2970] (ab327111)

Lane 2:

Human recombinant Laminin-111

Lane 3:

Human recombinant Laminin-211

Lane 4:

Human recombinant Laminin-411

Lane 5:

Human recombinant Laminin-511

Lane 6:

Human recombinant Laminin-521

Lane 7:

Human recombinant Laminin-332

Predicted band size: 198.04 kDa

false

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LAMB1 Antibody [CL2970] (AB327111)

Immunohistochemical staining of human lymph node using ab327111 at 1 : 50–1 : 200 dilution, showing absence of immunoreactivity in lymphoid cells (negative control).

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

CL2970

Isotype

IgG1

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human LAMB1.

P07942

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Ambient - Can Ship with Ice

적절한 단기 보관 조건

-20°C

적절한 장기 보관 조건

-20°C

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of the cerebral cortex (PubMed : 23472759). It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons (By similarity). Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface (By similarity). As a subunit of laminin-1 (also known as laminin-111 or EHS laminin), it is involved in the stimulation of agrin-induced receptor clustering through a MuSK-independent pathway (By similarity).

See full target information LAMB1

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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