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AB270339

Anti-LECT2 antibody [EPR22049-87] - BSA and Azide free (Detector)

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Rabbit Recombinant Monoclonal LECT2 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.
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Sandwich ELISA - Anti-LECT2 antibody [EPR22049-87] - BSA and Azide free (Detector) (AB270339)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-LECT2 antibody [EPR22049-87] - BSA and Azide free (Detector) (AB270339)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab269554).

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR22049-87

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB269554

Human LECT2 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human LECT2 ELISA Kit (AB269554)

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Sample Prep & Detection Kits

AB102899

PE/Cy5.5® Conjugation Kit - Lightning-Link®

Flow Cytometry - PE/Cy5.5® Conjugation Kit - Lightning-Link® (AB102899)

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Sample Prep & Detection Kits

AB269889

Europium Conjugation Kit

Dot Blot - Europium Conjugation Kit (AB269889)

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Primary Antibodies

AB259772

Anti-Peptide YY/PYY antibody [EPR21011-57] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-Peptide YY/PYY antibody [EPR21011-57] - BSA and Azide free (Detector) (AB259772)

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Primary Antibodies

AB242932

Anti-S100A9 antibody [EPR20066-233] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-S100A9 antibody [EPR20066-233] - BSA and Azide free (Detector) (AB242932)

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  • 0
Primary Antibodies

AB244722

Anti-IL-20 antibody [EPR20756-1] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-IL-20 antibody [EPR20756-1] - BSA and Azide free (Capture) (AB244722)

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  • 0
Primary Antibodies

AB245091

Anti-alpha smooth muscle Actin antibody [EPR20062-77] - BSA and Azide free (Detector)

RabMAb|Recombinant

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab270339 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human LECT2. The recommended pair for sandwich ELISA is:
Capture: ab270338, Human LECT2 Capture Antibody (unconjugated)
Detector: ab270339, Human LECT2 Detector Antibody (unconjugated)
The reference range value is 1.5625 - 100 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The target 'LECT2' also known as leukocyte cell-derived chemotaxin 2 is a 16 kDa protein. It plays a role in immune response and signaling by acting as a chemotactic factor for neutrophils. LECT2 is a secreted protein primarily expressed in the liver and found in circulation in the bloodstream. It has been associated with acute-phase response and inflammation.
Biological function summary

LECT2 contributes to tissue regeneration liver function and modulation of immune responses. It is not known to be part of a larger protein complex but interacts with multiple receptor types on cell surfaces. LECT2 can inhibit mitogen-activated protein kinase (MAPK) pathway by binding to specific receptors affecting cell proliferation and survival. It also plays a role in metabolic processes.

Pathways

The LECT2 protein influences the MAPK and JNK pathways impacting cellular stress responses and inflammatory signaling. Its interactions with other proteins involve MAPK family members like p38 and ERK. These pathways regulate various cellular activities such as proliferation apoptosis and cytokine production positioning LECT2 as a modulator of cellular signaling networks.

LECT2 has strong connections to liver-related conditions such as fatty liver disease and liver fibrosis. It also associates with conditions like amyloid A kidney amyloidosis. In these diseases LECT2 interacts with inflammatory cytokines like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) which play roles in inflammation and fibrosis. These interactions can alter disease outcomes and affect therapeutic strategies targeting these inflammatory pathways.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation (PubMed : 9524238). Does not show metalloendopeptidase activity (PubMed : 27334921).
See full target information Leukocyte cell-derived chemotaxin-2

대체 명칭 보기

Leukocyte cell-derived chemotaxin-2, LECT-2, hLECT2, LECT2
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Product promise

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