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AB89835

Anti-LECT2 antibody [MM0449-4B24]

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(2 제품이 사용된 논문 )

Mouse Monoclonal LECT2 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human Leukocyte cell-derived chemotaxin-2.
1 이미지
Western blot - Anti-LECT2 antibody [MM0449-4B24] (AB89835)
  • WB

Supplier Data

Western blot - Anti-LECT2 antibody [MM0449-4B24] (AB89835)

All lanes:

Western blot - Anti-LECT2 antibody [MM0449-4B24] (ab89835)

Predicted band size: 16 kDa

false

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

MM0449-4B24

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human Leukocyte cell-derived chemotaxin-2.

O14960

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대체품

Primary Antibodies

AB119429

Anti-LECT2 antibody [OTI2A11]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LECT2 antibody [OTI2A11] (AB119429)

  • 0
  • 0

보완 제품

Assay Kits

AB269554

Human LECT2 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human LECT2 ELISA Kit (AB269554)

  • 0
  • 0
Proteins & Peptides

AB188467

Recombinant Human LECT2 protein

SDS-PAGE - Recombinant Human LECT2 protein (AB188467)

  • 0
  • 0
Primary Antibodies

AB318152

Anti-VE Cadherin antibody [RM2022]

BOND RX™ Validated|20ul selling size|Recombinant|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-VE Cadherin antibody [RM2022] (AB318152)

  • 0
  • 0
Primary Antibodies

AB215203

Anti-cleaved N-terminal GSDMD antibody [EPR20829-408]

RabMAb|Recombinant|20ul selling size

Western blot - Anti-cleaved N-terminal GSDMD antibody [EPR20829-408] (AB215203)

  • 5
  • 4
Primary Antibodies

AB179515

Anti-pro Caspase-1 + p10 + p12 antibody [EPR16883]

RabMAb|Recombinant|20ul selling size

Western blot - Anti-pro Caspase-1 + p10 + p12 antibody [EPR16883] (AB179515)

  • 3
  • 3
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and sterile filtered through a 0.2 µm filter.
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The target 'LECT2' also known as leukocyte cell-derived chemotaxin 2 is a 16 kDa protein. It plays a role in immune response and signaling by acting as a chemotactic factor for neutrophils. LECT2 is a secreted protein primarily expressed in the liver and found in circulation in the bloodstream. It has been associated with acute-phase response and inflammation.
Biological function summary

LECT2 contributes to tissue regeneration liver function and modulation of immune responses. It is not known to be part of a larger protein complex but interacts with multiple receptor types on cell surfaces. LECT2 can inhibit mitogen-activated protein kinase (MAPK) pathway by binding to specific receptors affecting cell proliferation and survival. It also plays a role in metabolic processes.

Pathways

The LECT2 protein influences the MAPK and JNK pathways impacting cellular stress responses and inflammatory signaling. Its interactions with other proteins involve MAPK family members like p38 and ERK. These pathways regulate various cellular activities such as proliferation apoptosis and cytokine production positioning LECT2 as a modulator of cellular signaling networks.

LECT2 has strong connections to liver-related conditions such as fatty liver disease and liver fibrosis. It also associates with conditions like amyloid A kidney amyloidosis. In these diseases LECT2 interacts with inflammatory cytokines like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) which play roles in inflammation and fibrosis. These interactions can alter disease outcomes and affect therapeutic strategies targeting these inflammatory pathways.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation (PubMed : 9524238). Does not show metalloendopeptidase activity (PubMed : 27334921).
See full target information Leukocyte cell-derived chemotaxin-2

대체 명칭 보기

Leukocyte cell-derived chemotaxin-2, LECT-2, hLECT2, LECT2
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Biomedical reports 6:167-174 PubMed28357068

2017

Differential proteomics analysis of liver failure in peripheral blood mononuclear cells using isobaric tags for relative and absolute quantitation.

Applications

Unspecified application

Species

Unspecified reactive species

Hua Lin,Qiu-Pei Tan,Wei-Guo Sui,Wen-Biao Chen,Wu-Jian Peng,Xing-Chao Liu,Yong Dai

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 18:565-72 PubMed23937207

2013

iTRAQ-based proteomics reveals novel biomarkers of osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Daiki Ikeda,Hiroshi Ageta,Kunihiro Tsuchida,Harumoto Yamada
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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