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AB230864

Anti-LENG8 antibody

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Rabbit Polyclonal LENG8 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human LENG8 aa 450-700.

대체 명칭 보기

KIAA1932, LENG8, Leukocyte receptor cluster member 8

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LENG8 antibody (AB230864)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LENG8 antibody (AB230864)

Formalin-fixed, paraffin-embedded human thymus tissue stained for LENG8 using ab230864 at 5 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LENG8 antibody (AB230864)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LENG8 antibody (AB230864)

Formalin-fixed, paraffin-embedded human prostate tissue stained for LENG8 using ab230864 at 5 μg/ml in immunohistochemical analysis.

Western blot - Anti-LENG8 antibody (AB230864)
  • WB

Supplier Data

Western blot - Anti-LENG8 antibody (AB230864)

All lanes:

Western blot - Anti-LENG8 antibody (ab230864) at 1/1000 dilution

Lane 1:

Human fetal heart lysate

Lane 2:

Human kidney lysate

Predicted band size: 86 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human LENG8 aa 450-700. The exact immunogen used to generate this antibody is proprietary information.

Q96PV6

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보완 제품

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Primary Antibodies

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Primary Antibodies

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Primary Antibodies

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Anti-LAMP1 antibody [EPR24395-31] - Lysosome Marker

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  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
Preservative: 0.02% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

LENG8 also known as Leukocyte Receptor Cluster Member 8 is a protein that plays an important role in immune signaling. The molecular weight of LENG8 is approximately 25 kDa. LENG8 shows expression mainly in immune-related tissues like the spleen and lymph nodes indicating its role in the immune system. Its expression patterns suggest a functional role in immune cell interaction and signaling.
Biological function summary

The actions of LENG8 are tied to immune cell interaction within the leukocyte receptor cluster. It does not work as an isolated protein but participates as part of a broader protein network. This cluster involves several receptors linked to immune modulation. LENG8 possibly influences the regulation of immune responses contributing to maintaining immune homeostasis.

Pathways

Researchers have connected LENG8 to immune-related signaling pathways such as the cytokine receptor signaling pathway. Its involvement here suggests interactions with various cytokine receptors and other leukocyte receptors. These interactions place LENG8 in the broader context of immune cell activation and communication potentially interacting with proteins such as IL-2 and IL-4 which are key players in controlling immune responses.

LENG8's role in immune regulation implies a potential connection to autoimmune diseases like rheumatoid arthritis. Dysfunction or altered expression of LENG8 might influence disease progression due to its impact on immune cell signaling. In rheumatoid arthritis proteins such as TNF-alpha and IL-6 which regulate inflammatory responses might exhibit altered interactions with the pathways that involve LENG8 contributing to the disease pathology.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information LENG8
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of clinical investigation 134: PubMed38885336

2024

The IFITM5 mutation in osteogenesis imperfecta type V is associated with an ERK/SOX9-dependent osteoprogenitor differentiation defect.

Applications

Unspecified application

Species

Unspecified reactive species

Ronit Marom,I-Wen Song,Emily C Busse,Megan E Washington,Ava S Berrier,Vittoria C Rossi,Laura Ortinau,Youngjae Jeong,Ming-Ming Jiang,Brian C Dawson,Mary Adeyeye,Carolina Leynes,Caressa D Lietman,Bridget M Stroup,Dominyka Batkovskyte,Mahim Jain,Yuqing Chen,Racel Cela,Alexis Castellon,Alyssa A Tran,Isabel Lorenzo,D Nicole Meyers,Shixia Huang,Alicia Turner,Vinitha Shenava,Maegen Wallace,Eric Orwoll,Dongsu Park,Catherine G Ambrose,Sandesh Cs Nagamani,Jason D Heaney,Brendan H Lee
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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