JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB127545

Anti-LHX5 antibody

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Rabbit Polyclonal LHX5 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human LHX5 aa 50-300.

대체 명칭 보기

LIM/homeobox protein Lhx5, LIM homeobox protein 5, LHX5

1 이미지
Western blot - Anti-LHX5 antibody (AB127545)
  • WB

Unknown

Western blot - Anti-LHX5 antibody (AB127545)

10% SDS PAGE

All lanes:

Western blot - Anti-LHX5 antibody (ab127545) at 1/1000 dilution

All lanes:

A431 whole cell lysate at 30 µg

Predicted band size: 38 kDa,39 kDa,44 kDa,49 kDa

true

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human LHX5 aa 50-300. The exact immunogen used to generate this antibody is proprietary information.

Q9H2C1

style
left-column

대체품

Primary Antibodies

AB187975

Anti-LHX5 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LHX5 antibody (AB187975)

  • 0
  • 0

보완 제품

Primary Antibodies

AB177487

Anti-NeuN antibody [EPR12763] - Neuronal Marker

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Immunohistochemistry (Frozen sections) - Anti-NeuN antibody [EPR12763] - Neuronal Marker (AB177487)

  • 5
  • 75
Primary Antibodies

AB183032

Anti-TBR1 antibody [EPR8138(2)]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Frozen sections) - Anti-TBR1 antibody [EPR8138(2)] (AB183032)

  • 5
  • 6
Primary Antibodies

AB309139

Anti-CUX1+CUX2 antibody [EPR26509-154]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CUX1+CUX2 antibody [EPR26509-154] (AB309139)

  • 5
  • 2
Primary Antibodies

AB21990

Anti-Otx1 + Otx2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Otx1 + Otx2 antibody (AB21990)

  • 5
  • 11
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Xenopus laevis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

LHX5 also known as LIM Homeobox 5 is a transcription factor with a molecular mass of approximately 45 kDa. It plays an important role in regulating gene expression by binding to DNA sequences. This protein is mainly expressed in the central nervous system particularly in the developing brain and spinal cord where it influences neuronal differentiation and development.
Biological function summary

LHX5 contributes significantly to the development of the forebrain and hippocampus. It forms part of a molecular complex that controls the transcription of genes necessary for proper neuronal placement and differentiation. Through its interaction with co-factors LHX5 modulates the expression of downstream target genes involved in neurogenesis.

Pathways

LHX5 plays a role in Wnt signaling and neurodevelopmental pathways. It interacts with other proteins such as LHX1 and LHX2 helping to fine-tune the expression of genes involved in brain patterning and neural circuit formation. These interactions influence critical developmental processes ensuring appropriate neural network establishment.

LHX5 is linked to neurological conditions such as epilepsy and intellectual disability. Mutations or dysregulation in LHX5 may contribute to abnormal neural development leading to these disorders. Additionally LHX5 interacts with other proteins implicated in these conditions such as PAX6 potentially affecting the severity or outcome of the disease state.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.
See full target information LHX5
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Investigative ophthalmology & visual science 62:22 PubMed34156427

2021

Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaofen Jin,Juanjuan Zhang,Qiuzi Yi,Feilong Meng,Jialing Yu,Yanchun Ji,Jun Q Mo,Yi Tong,Pingping Jiang,Min-Xin Guan
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com