AB235524

Anti-LIX1 antibody

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Rabbit Polyclonal LIX1 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human LIX1.

대체 명칭 보기

C5orf11, LIX1, Protein limb expression 1 homolog

1 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LIX1 antibody (AB235524)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LIX1 antibody (AB235524)

Paraffin-embedded human placenta tissue stained for LIX1 using ab235524 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Full Length Protein corresponding to Human LIX1.

Q8N485

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein G

Purification 관련 사항

Purity >95%

보관 버퍼

pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

LIX1 also known as Limb and CNS Expressed 1 represents a protein with a mass of approximately 18 kDa. It expresses primarily in the central nervous system and limb tissues. This protein exhibits particular importance in developmental processes. Structural studies reveal that LIX1 may play a role in molecular signaling involving interactions with other intracellular proteins to facilitate its function.

Biological function summary

LIX1 supports the regulation of cell proliferation and differentiation particularly during early embryonic development. Evidence suggests that it may interact with cellular scaffolding proteins supporting its integration into larger protein complexes. LIX1 ensures the precision of cellular growth and structural development acting as a potential modulator of morphogenetic signals.

Pathways

Studies suggest that LIX1 participates in the Wnt signaling pathway and the Hedgehog signaling pathway. These pathways are fundamental in the regulation of developmental processes such as tissue patterning and cell fate determination. LIX1's involvement with these pathways aligns it closely with other proteins like β-catenin in the Wnt pathway and GLI family proteins in the Hedgehog pathway facilitating finely tuned biological responses.

Research has connected LIX1 with colorectal cancer and limb development disorders. Altered expression or dysfunction of LIX1 may contribute to improper cellular growth regulation thereby affecting these conditions. In the context of limb development disorders LIX1 may work in conjunction with other proteins such as Sonic Hedgehog (SHH) important for the proper formation of limb structures. Understanding LIX1's role in these diseases could help further identify therapeutic targets.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

See full target information LIX1

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cancer medicine 12:5035-5054 PubMed36205357

2022

Systemic analysis of the DNA replication regulator origin recognition complex in lung adenocarcinomas identifies prognostic and expression significance.

Applications

Unspecified application

Species

Unspecified reactive species

Min Tang,Juan Chen,Tian Zeng,Dong-Mei Ye,Yu-Kun Li,Juan Zou,Yu-Ping Zhang

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-LIX1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LIX1 antibody (AB235524)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (1)

Product promise