AB232884

Anti-LOXL3 antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal LOXL3 antibody. Suitable for WB, IHC-P and reacts with Mouse samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Mouse Loxl3 aa 500-750.

대체 명칭 보기

Lor2, Loxl3, Lysyl oxidase homolog 3, Lysyl oxidase-like protein 3, Lysyl oxidase-related protein 2

6 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse lung tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse spleen tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse pancreas tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Formalin-fixed, paraffin-embedded mouse cerebrum tissue stained for LOXL3 with ab232884 at 20 μg/ml in immunohistochemical analysis.

Secondary used : HRP-Linked Goat anti-Rabbit IgG polyclonal at 2 μg/ml. DAB staining.

Supplier Data

Western blot - Anti-LOXL3 antibody (AB232884)

All lanes:

Western blot - Anti-LOXL3 antibody (ab232884) at 3 µg/mL

All lanes:

Mouse serum

Secondary

All lanes:

HRP-linked Guinea pig anti-Rabbit at 1/2000 dilution

Predicted band size: 83 kDa

false

Supplier Data

Western blot - Anti-LOXL3 antibody (AB232884)

All lanes:

Western blot - Anti-LOXL3 antibody (ab232884) at 2 µg/mL

All lanes:

Recombinant mouse LOXL3 protein

Predicted band size: 83 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Mouse Loxl3 aa 500-750. The exact immunogen used to generate this antibody is proprietary information.

Q9Z175

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

Purification 관련 사항

Antigen-specific affinity chromatography followed by Protein A affinity chromatography.

보관 버퍼

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins (PubMed : 26954549). Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in precursors of elastin and different types of collagens, a prerequisite in the formation of cross-links between collagens and elastin (PubMed : 26307084). Required for somite boundary formation by catalyzing oxidation of fibronectin (FN1), enhancing integrin signaling in myofibers and their adhesion to the myotendinous junction (MTJ) (PubMed : 26954549). Acts as a regulator of inflammatory response by inhibiting differentiation of naive CD4(+) T-cells into T-helper Th17 or regulatory T-cells (Treg) : acts by interacting with STAT3 in the nucleus and catalyzing both deacetylation and oxidation of lysine residues on STAT3, leading to disrupt STAT3 dimerization and inhibit STAT3 transcription activity (PubMed : 28065600). Oxidation of lysine residues to allysine on STAT3 preferentially takes place on lysine residues that are acetylated (By similarity). Also able to catalyze deacetylation of lysine residues on STAT3 (By similarity).

See full target information Loxl3

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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Environmental toxicology 37:2540-2551 PubMed35841383

2022

LOXL3-promoted hepatocellular carcinoma progression via promotion of Snail1/USP4-mediated epithelial-mesenchymal transition.

Applications

Unspecified application

Species

Unspecified reactive species

Rong Li,Runze Shang,Shunle Li,Yifan Ren,Lin Shen,Longbao Yang,Shuo Chen,Xi Chen,Junhui Li,Meng Xu

PLoS genetics 15:e1008196 PubMed31173582

2019

Cyclophilin B control of lysine post-translational modifications of skin type I collagen.

Applications

Unspecified application

Species

Unspecified reactive species

Masahiko Terajima,Yuki Taga,Wayne A Cabral,Ying Liu,Masako Nagasawa,Noriko Sumida,Yukako Kayashima,Prashant Chandrasekaran,Lin Han,Nobuyo Maeda,Irina Perdivara,Shunji Hattori,Joan C Marini,Mitsuo Yamauchi

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-LOXL3 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LOXL3 antibody (AB232884)

Western blot - Anti-LOXL3 antibody (AB232884)

Western blot - Anti-LOXL3 antibody (AB232884)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (2)

Product promise