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AB317131

Anti-LRP4 antibody [HL2080]

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Rabbit Recombinant Monoclonal LRP4 antibody. Suitable for ICC/IF, WB and reacts with Rat, Human, Mouse samples. Immunogen corresponding to Recombinant Fragment Protein within Mouse Lrp4.

대체 명칭 보기

Kiaa0816, Lrp4, Low-density lipoprotein receptor-related protein 4, LRP-4, LDLR dan

5 이미지
Immunocytochemistry/ Immunofluorescence - Anti-LRP4 antibody [HL2080] (AB317131)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-LRP4 antibody [HL2080] (AB317131)

ab317131 detects LRP4 protein at cell membrane and nucleus by immunofluorescent analysis.
Sample : DIV9 rat E18 primary hippocampal neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green : LRP4 stained by ab317131 diluted at 1 : 250.
Red : Tau a axon marker stained by Tau antibody diluted at 1 : 500.
Blue : Fluoroshield with DAPI.

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)
  • WB

Supplier Data

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)

Whole cell extract (30 ug) was separated by 5% SDS-PAGE and the membrane was blotted with ab317131 diluted at 1 : 1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

All lanes:

Western blot - Anti-LRP4 antibody [HL2080] (ab317131) at 1/1000 dilution

All lanes:

PC-3 whole cell extract at 30 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

false

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)
  • WB

Supplier Data

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)

Rat tissue extract (50 ug) was separated by 5% SDS-PAGE and the membrane was blotted with ab317131 diluted at 1 : 500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody and the signal was developed with Trident ECL plus-Enhanced.

All lanes:

Western blot - Anti-LRP4 antibody [HL2080] (ab317131) at 1/500 dilution

All lanes:

Rat brain tissue extract at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

true

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)
  • WB

Supplier Data

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)

Mouse tissue extract (50 ug) was separated by 5% SDS-PAGE and the membrane was blotted with ab317131 diluted at 1 : 1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody and the signal was developed with Trident ECL plus-Enhanced.

All lanes:

Western blot - Anti-LRP4 antibody [HL2080] (ab317131) at 1/1000 dilution

All lanes:

Mouse lung tissue extract at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

true

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)
  • WB

Supplier Data

Western blot - Anti-LRP4 antibody [HL2080] (AB317131)

Mouse tissue extract (50 ug) was separated by 5% SDS-PAGE and the membrane was blotted with ab317131 diluted at 1 : 1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

All lanes:

Western blot - Anti-LRP4 antibody [HL2080] (ab317131) at 1/1000 dilution

All lanes:

Mouse liver tissue extract at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

HL2080

Isotype

IgG

Carrier free

No

Reacts with

Human, Mouse, Rat

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Mouse Lrp4.

Q8VI56

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보완 제품

Primary Antibodies

AB192583

Anti-MUSK (phospho Y755) antibody

Western blot - Anti-MUSK (phospho Y755) antibody (AB192583)

  • 3
  • 1
Primary Antibodies

AB228488

Anti-MUSK antibody - N-terminal

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUSK antibody - N-terminal (AB228488)

  • 0
  • 0
Primary Antibodies

AB129002

Anti-Vinculin antibody [EPR8185] - Loading Control

20ul selling size|RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Vinculin antibody [EPR8185] - Loading Control (AB129002)

  • 5
  • 21
Primary Antibodies

AB183591

Anti-Acetylcholinesterase antibody [EPR18978]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Frozen sections) - Anti-Acetylcholinesterase antibody [EPR18978] (AB183591)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/250", "ICCIF-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" } } }
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제품 세부 정보

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형
Liquid
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes. Plays an essential role in the process of digit differentiation (PubMed : 16517118).
See full target information Lrp4
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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