JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB121447

Anti-MCEMP1 antibody

Be the first to review this product! 리뷰 제출

|

(2 제품이 사용된 논문 )

Rabbit Polyclonal MCEMP1 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human MCEMP1 aa 100-200.

대체 명칭 보기

C19orf59, MCEMP1, Mast cell-expressed membrane protein 1

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MCEMP1 antibody (AB121447)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MCEMP1 antibody (AB121447)

ab121447, at 1/150 dilution, staining MCEMP1 in paraffin-embedded Human bone marrow tissue by Immunohistochemistry, showing strong cytoplasmic positivity in bone marrow poietic cells.

Western blot - Anti-MCEMP1 antibody (AB121447)
  • WB

Unknown

Western blot - Anti-MCEMP1 antibody (AB121447)

All lanes:

Western blot - Anti-MCEMP1 antibody (ab121447) at 1/250 dilution

Lane 1:

Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10

Lane 2:

Negative control (vector only transfected HEK293T lysate)

Lane 3:

Over-expression Lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells)

Predicted band size: 21 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human MCEMP1 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

Q8IX19

style
left-column

대체품

Primary Antibodies

AB188572

Anti-MCEMP1 antibody [EPR14393] - C-terminal

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MCEMP1 antibody [EPR14393] - C-terminal (AB188572)

  • 0
  • 0

보완 제품

Assay Kits

AB313991

Human MCEMP1 ELISA Kit

Sandwich ELISA - Human MCEMP1 ELISA Kit (AB313991)

  • 0
  • 0
Primary Antibodies

AB236898

Anti-Slc6a6/Taut antibody

Immunocytochemistry/ Immunofluorescence - Anti-Slc6a6/Taut antibody (AB236898)

  • 4
  • 1
Primary Antibodies

AB117806

Anti-LASP1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LASP1 antibody (AB117806)

  • 0
  • 0
Primary Antibodies

AB208687

Anti-FGF2 antibody [EPR20145-219]

20ul selling size|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-FGF2 antibody [EPR20145-219] (AB208687)

  • 5
  • 3
Primary Antibodies

AB302532

Anti-FOLR2 antibody [EPR25731-70]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOLR2 antibody [EPR25731-70] (AB302532)

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p>Use buffer at pH 6 for antigen retrieval.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

MCEMP1 also known as Mast Cell Expressed Membrane Protein 1 is a protein that plays an important role in cellular functions. The protein has a molecular mass of approximately 17 kDa. MCEMP1 is mainly expressed on the cell membranes of mast cells which are involved in immune system responses. This expression pattern suggests MCEMP1's involvement in processes closely tied to mast cell biology.
Biological function summary

This protein has significant roles in mast cell activation and signal transduction. MCEMP1 is not part of a known protein complex but it influences mast cell degranulation where cells release histamine and other mediators. This activity places MCEMP1 as an influential protein impacting the body's response to allergens and infections.

Pathways

MCEMP1 is important for pathways related to immune system signaling and allergic responses. In the immune signaling pathway MCEMP1 impacts mast cell mediator release interacting with proteins such as FcεRI a high-affinity receptor for IgE. Another related pathway involves inflammatory responses where MCEMP1 further regulates signals that contribute to the body's defense mechanism against pathogens.

MCEMP1 is linked to allergic reactions and asthma. These conditions often result from excessive activation of mast cells where MCEMP1 plays a regulatory function. The protein interacts closely with FcεRI in asthma a chronic condition characterized by airway inflammation. Understanding the role of MCEMP1 in these disorders helps in exploring potential therapeutic targets for managing allergic conditions.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

See full target information MCEMP1
style
left-column

제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in physiology 12:714785 PubMed34408668

2021

Upregulation of Calcium Homeostasis Modulators in Contractile-To-Proliferative Phenotypical Transition of Pulmonary Arterial Smooth Muscle Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Marisela Rodriguez,Jiyuan Chen,Pritesh P Jain,Aleksandra Babicheva,Mingmei Xiong,Jifeng Li,Ning Lai,Tengteng Zhao,Moises Hernandez,Angela Balistrieri,Sophia Parmisano,Tatum Simonson,Ellen Breen,Daniela Valdez-Jasso,Patricia A Thistlethwaite,John Y-J Shyy,Jian Wang,Joe G N Garcia,Ayako Makino,Jason X-J Yuan

IUBMB life 71:956-968 PubMed30883005

2019

Silence of long noncoding RNA NEAT1 exerts suppressive effects on immunity during sepsis by promoting microRNA-125-dependent MCEMP1 downregulation.

Applications

Unspecified application

Species

Unspecified reactive species

Jian-Xin Chen,Xiong Xu,Sen Zhang
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com