AB87639

Anti-Melatonin Receptor 1A/MTNR1A antibody

Name: Anti-Melatonin Receptor 1A/MTNR1A antibody
Brand: Abcam Limited
SKU: AB87639
Rating: 4 (2 reviews)

(2 리뷰들)

(14 제품이 사용된 논문 )

Goat Polyclonal Melatonin Receptor 1A/MTNR1A antibody. Suitable for WB and reacts with Rat samples. Cited in 14 publications. Immunogen corresponding to Synthetic Peptide within Human Melatonin receptor type 1A aa 100-150.

1 이미지

Unknown

Western blot - Anti-Melatonin Receptor 1A/MTNR1A antibody (AB87639)

All lanes:

Western blot - Anti-Melatonin Receptor 1A/MTNR1A antibody (ab87639) at 0.1 µg/mL

All lanes:

Rat Retina lysate at 35 µg

Predicted band size: 39 kDa

Observed band size: 45 kDa

true

Exposure time: 1hr

주요 정보

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat

Applications

applications

Immunogen

Synthetic Peptide within Human Melatonin receptor type 1A aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

P48039

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.1-0.3 µg/mL", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

Purification 관련 사항

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

보관 버퍼

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. Possibly involved in sleep induction, by melatonin activation of the potassium channel KCNMA1/BK and the dissociation of G-beta and G-gamma subunits, thereby decreasing synaptic transmission (By similarity).

See full target information Melatonin receptor type 1A

대체 명칭 보기

Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A

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제품이 사용된 논문 (14)

Recent publications for all applications. Explore the 전체 목록 and refine your search

BMC genomics 26:242 PubMed40082769

2025

Transcriptomic and proteomic analyses of sclera in lens-induced myopic guinea pigs.

Applications

Unspecified application

Species

Unspecified reactive species

He-Yan Li,Xu-Han Shi,Li Dong,Chu-Yao Yu,Yi-Tong Li,Rui-Heng Zhang,Wen-Da Zhou,Hao-Tian Wu,Jost B Jonas,Wen-Bin Wei

International journal of immunopathology and pharmacology 39:3946320251318147 PubMed39936565

2025

Melatonin alleviates oral epithelial cell inflammation via Keap1/Nrf2 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Nan Zhang,Wenjing Wang,Rongxia Zhang,Yaxuan Liu,Yamei Wang,Yang Bai,Chencong Li

International journal of molecular sciences 24: PubMed37569373

2023

The Photoperiod-Driven Cyclical Secretion of Pineal Melatonin Regulates Seasonal Reproduction in Geese ().

Applications

Unspecified application

Species

Unspecified reactive species

Qiang Bao,Wang Gu,Lina Song,Kaiqi Weng,Zhengfeng Cao,Yu Zhang,Yang Zhang,Ting Ji,Qi Xu,Guohong Chen

Animals : an open access journal from MDPI 13: PubMed37370427

2023

Photoperiod Induces DNA Methylation Changes in the Melatonin Receptor 1A Gene in Ewes.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoyun He,Wei Wang,Wei Sun,Mingxing Chu

Journal of pineal research 72:e12787 PubMed35133672

2022

Activation of melatonin receptor 1 by CRISPR-Cas9 activator ameliorates cognitive deficits in an Alzheimer's disease mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Hanseul Park,Jongpil Kim

Animals : an open access journal from MDPI 11: PubMed34201764

2021

Testicular Melatonin and Its Pathway in Roe Deer Bucks () during Pre- and Post-Rut Periods: Correlation with Testicular Involution.

Applications

Unspecified application

Species

Unspecified reactive species

Alberto Elmi,Nadia Govoni,Augusta Zannoni,Martina Bertocchi,Chiara Bernardini,Monica Forni,Domenico Ventrella,Maria Laura Bacci

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 256:110634 PubMed34119649

2021

The probiotic Lactobacillus rhamnosus mimics the dark-driven regulation of appetite markers and melatonin receptors' expression in zebrafish (Danio rerio) larvae: Understanding the role of the gut microbiome.

Applications

Unspecified application

Species

Unspecified reactive species

Esmail Lutfi,Danilo Basili,Silvia Falcinelli,Luis Morillas,Oliana Carnevali,Encarnación Capilla,Isabel Navarro

Frontiers in physiology 11:408 PubMed32435203

2020

Photoperiod Affects Harderian Gland Morphology and Secretion in Female : Autophagy, Apoptosis, and Mitochondria.

Applications

Unspecified application

Species

Unspecified reactive species

Zhe Wang,Jin-Hui Xu,Jun-Jie Mou,Xiao-Tong Kong,Ming Wu,Hui-Liang Xue,Lai-Xiang Xu

RSC advances 10:11264-11273 PubMed35495343

2020

A study of the mechanism of small-molecule soybean-protein-derived peptide supplement to promote sleep in a mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Guofu Yi,Bushra Safdar,Yihao Zhang,You Li,Xinqi Liu

International journal of molecular sciences 21: PubMed31947744

2020

Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage.

Applications

Unspecified application

Species

Unspecified reactive species

Kelly Dong,Earl Goyarts,Antonella Rella,Edward Pelle,Yung Hou Wong,Nadine Pernodet

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Melatonin Receptor 1A/MTNR1A antibody

Western blot - Anti-Melatonin Receptor 1A/MTNR1A antibody (AB87639)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (14)

Product promise