AB326814
Mouse Monoclonal Sialoadhesin/CD169 antibody - conjugated to mFluor™ UV375. Suitable for Flow Cyt and reacts with Human samples.
1 이미지
![Other - mFluor™ UV375 Anti-CD169 antibody [7-239] (AB326814)](https://content.abcam.com/products/images/mfluor-uv375-cd169-antibody-7-239-ab326814--other-img461133.jpg/_jcr_content/renditions/webp-768.webp)
- Other
Supplier Data
Other - mFluor™ UV375 Anti-CD169 antibody [7-239] (AB326814)
Spectrum for mFluor™ UV375 Anti-CD169 antibody [7-239]
보완 제품
![Flow Cytometry - Alexa Fluor® 488 Anti-CD4 antibody [EPR20122] (AB252149)](https://content.abcam.com/products/images/alexa-fluor-488-cd4-antibody-epr20122-ab252149--flow-cytometry-img13566.jpg)
![Flow Cytometry - Alexa Fluor® 594 Anti-CD11b antibody [M1/70] (AB312914)](https://content.abcam.com/products/images/alexa-fluor-594-cd11b-antibody-m1-70-ab312914--flow-cytometry-img417056.jpg)
![Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 488 Anti-CD11c antibody [KB90] (AB313900)](https://content.abcam.com/products/images/alexa-fluor-488-cd11c-antibody-kb90-ab313900--immunocytochemistry-immunofluorescence-img419304.jpg)
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "1/20", "FlowCyt-species-notes": "<p></p>" } } }
특성 및 보관 정보
제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.2% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze
제품 프로토콜
For this product, it's our understanding that no specific protocols are required. You can visit:
- Visit the General protocols
- Visit the Troubleshooting
타겟 정보
Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response (PubMed : 12940982, PubMed : 33489013). Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs) (PubMed : 28129379). In turn, enhances macrophage-to-T-cell transmission of several viruses including HIV-1 or SARS-CoV-2 (PubMed : 28129379, PubMed : 34782760). Acts as an endocytic receptor mediating clathrin dependent endocytosis. Preferentially binds to alpha-2,3-linked sialic acid (PubMed : 12940982). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. Plays a role in the inhibition of antiviral innate immune by promoting TBK1 degradation via TYROBP and TRIM27-mediated ubiquitination (PubMed : 26358190).. (Microbial infection) Facilitates viral cytoplasmic entry into activated dendritic cells via recognition of sialylated gangliosides pesent on viral membrane.
대체 명칭 보기
CD169, SN, SIGLEC1, Sialoadhesin, Sialic acid-binding Ig-like lectin 1, Siglec-1
Product promise
저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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