AB326809
Mouse Monoclonal CD27 antibody - conjugated to mFluor™ UV375. Suitable for Flow Cyt and reacts with Human samples.
1 이미지
![Other - mFluor™ UV375 Anti-CD27 antibody [LT27] (AB326809)](https://content.abcam.com/products/images/mfluor-uv375-cd27-antibody-lt27-ab326809--other-img461133.jpg/_jcr_content/renditions/webp-768.webp)
- Other
Supplier Data
Other - mFluor™ UV375 Anti-CD27 antibody [LT27] (AB326809)
Spectrum for mFluor™ UV375 Anti-CD27 antibody [LT27]
관련 conjugated 항체와 다양한 조성의 항체 (6)
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660 APC
APC Anti-CD27 antibody [LT27]
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519 FITC
FITC Anti-CD27 antibody [LT27]
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578 PE
PE Anti-CD27 antibody [LT27]
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778 PE/Cy7®
PE/Cy7® Anti-CD27 antibody [LT27]
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695 PerCP/Cy5.5®
PerCP/Cy5.5® Anti-CD27 antibody [LT27]
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mFluor™ Violet 450 Anti-CD27 antibody [LT27]
보완 제품
![Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 647 Anti-CD19 antibody [EPR5906] (AB196515)](https://content.abcam.com/products/images/alexa-fluor-647-cd19-antibody-epr5906-ab196515--immunocytochemistry-immunofluorescence-img70016.jpg)
![Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD45 antibody [EP322Y] (AB200315)](https://content.abcam.com/products/images/alexa-fluor-488-cd45-antibody-ep322y-ab200315--flow-cytometry-intracellular-img79307.jpg)
Primary Antibodies
AB305048
Alexa Fluor® 647 Anti-CD8 alpha antibody [CAL66]
BOND RX™ Validated|RabMAb|Recombinant
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD8 alpha antibody [CAL66] (AB305048)](https://content.abcam.com/products/images/alexa-fluor-647-cd8-alpha-antibody-cal66-ab305048--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img403317.jpg)
- 5
- 1
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD4 antibody [EPR6855] (AB196147)](https://content.abcam.com/products/images/alexa-fluor-647-cd4-antibody-epr6855-ab196147--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img179285.jpg)
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "1/20", "FlowCyt-species-notes": "<p></p>" } } }
특성 및 보관 정보
제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.2% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze
제품 프로토콜
For this product, it's our understanding that no specific protocols are required. You can visit:
- Visit the General protocols
- Visit the Troubleshooting
타겟 정보
Costimulatory immune-checkpoint receptor expressed at the surface of T-cells, NK-cells and B-cells which binds to and is activated by its ligand CD70/CD27L expressed by B-cells (PubMed : 28011863). The CD70-CD27 signaling pathway mediates antigen-specific T-cell activation and expansion which in turn provides immune surveillance of B-cells (PubMed : 28011863). Mechanistically, CD70 ligation activates the TRAF2-PTPN6 axis that subsequently inhibits LCK phosphorylation to promote phenotypic and transcriptional adaptations of T-cell memory (PubMed : 38354704). In addition, activation by CD70 on early progenitor cells provides a negative feedback signal to leukocyte differentiation during immune activation and thus modulates hematopoiesis (By similarity). Negatively regulates the function of Th2 lymphocytes in the adipose tissue (By similarity).
대체 명칭 보기
CD27, TNFRSF7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7
Product promise
저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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