AB326852
Mouse Monoclonal CD45 antibody - conjugated to mFluor™ UV375. Suitable for Flow Cyt and reacts with Human samples.
1 이미지
- Other
Supplier Data
Other - mFluor™ UV375 Anti-CD45RO antibody [UCHL1] (AB326852)
Spectrum for mFluor™ UV375 Anti-CD45RO antibody [UCHL1]
관련 conjugated 항체와 다양한 조성의 항체 (9)
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Anti-CD45RO antibody [UCHL1]
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660 APC
APC Anti-CD45R0 antibody [UCHL1]
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519 FITC
FITC Anti-CD45R0 antibody [UCHL1]
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519 FITC
FITC Anti-CD45RO antibody [UCHL1]
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578 PE
PE Anti-CD45R0 antibody [UCHL1]
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578 PE
PE Anti-CD45RO antibody [UCHL1]
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667 PE/Cy5®
PE/Cy5® Anti-CD45RO antibody [UCHL1]
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mFluor™ Violet 450 Anti-CD45RO antibody [UCHL1]
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704 redFluor™ 710
redFluor™ 710 Anti-CD45RO antibody [UCHL1]
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "1/20", "FlowCyt-species-notes": "<p></p>" } } }
특성 및 보관 정보
제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.2% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze
제품 프로토콜
For this product, it's our understanding that no specific protocols are required. You can visit:
- Visit the General protocols
- Visit the Troubleshooting
타겟 정보
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed : 35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). Interacts with CLEC10A at antigen presenting cell-T cell contact; CLEC10A on immature dendritic cells recognizes Tn antigen-carrying PTPRC/CD45 receptor on effector T cells and modulates T cell activation threshold to limit autoreactivity.. (Microbial infection) Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.
대체 명칭 보기
CD45, PTPRC, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, T200, L-CA
Product promise
저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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