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AB246926

Anti-MRI antibody

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Rabbit Polyclonal MRI antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human CYREN aa 1 to C-terminus.

대체 명칭 보기

C7orf49, MRI, CYREN, Cell cycle regulator of non-homologous end joining, Cell cycle regulator of NHEJ, Modulator of retrovirus infection homolog

5 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)

Formalin-fixed, paraffin-embedded human cerebral cortex tissue stained for MRI with ab246926 at a 1/50 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-MRI antibody (AB246926)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-MRI antibody (AB246926)

PFA fixed, Triton X-100 permeabilized U-251 MG (Human brain glioma cell line) cells labeling MRI using ab246926 at 4 μg/ml (green) in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)

Formalin-fixed, paraffin-embedded human pancreas tissue shows absence of immunoreactivity for MRI when incubated with ab246296 at a 1/50 dilution (negative control).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)

Formalin-fixed, paraffin-embedded human duodenum tissue stained for MRI with ab246926 at a 1/50 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRI antibody (AB246926)

Formalin-fixed, paraffin-embedded human prostate tissue stained for MRI with ab246926 at a 1/50 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human CYREN aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9BWK5

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보완 제품

Primary Antibodies

AB204515

Anti-Cdc34 antibody [EPR16808]

RabMAb|Recombinant|Trial Size

Flow Cytometry (Intracellular) - Anti-Cdc34 antibody [EPR16808] (AB204515)

  • 0
  • 0
Proteins & Peptides

AB140733

Recombinant Human MRI protein (His tag N-Terminus)

SDS-PAGE - Recombinant Human MRI protein (His tag N-Terminus) (AB140733)

  • 0
  • 0
Primary Antibodies

AB11575

Anti-Laminin antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Laminin antibody (AB11575)

  • 5
  • 74
Primary Antibodies

AB110301

Anti-HADHB antibody [5C3AB7]

Flow Cytometry - Anti-HADHB antibody [5C3AB7] (AB110301)

  • 0
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100</p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Magnetic Resonance Imaging (MRI) is not a protein or biological target in the traditional sense but is a powerful imaging technique used in the life sciences. MRI functions mechanically by generating strong magnetic fields and radio waves to produce detailed images of organs and tissues. It does not express any mass because it is an instrument not a biomolecule. MRI is widely used across many fields and is essential in hospitals and research settings. Despite not being a protein MRI relies on the interaction with hydrogen protons particularly prevalent in water and fat to provide high-resolution images of soft tissues.
Biological function summary

MRI provides critical insights into the structure and function of the human body by visualizing soft tissues in great detail. This technology plays a powerful role in identifying the complex anatomy of tissues and organs giving it a significant presence in medical diagnostics. MRI can assess functional aspects of biological processes through techniques like functional MRI (fMRI) which measures brain activity by detecting changes in blood flow. Though MRI is not a biological molecule or part of any specific complex it contributes substantially to biological research by helping understand tissue composition and organ dysfunctions.

Pathways

MRI significantly impacts the study of biological processes and pathways by allowing detailed observation of real-time physiological processes. MRI is indispensable in evaluating the pathways related to neurological and cardiovascular systems. For example it aids in the visualization of neural connections and the assessment of blood vessels offering insights into the dynamic processes within these networks. Despite not being directly involved with molecular pathways MRI complements studies involving proteins such as those implicated in neural signaling or cardiac muscle contractions by enabling precise structural and functional assessments.

MRI offers invaluable aid in diagnosing and monitoring various conditions including brain disorders and cardiovascular diseases. MRI’s high-resolution imaging helps identify abnormalities like tumors lesions or ischemic areas with precision often involving proteins like amyloid beta in Alzheimer's disease or troponin in conditions related to the heart. By visualizing disease progression or treatment impact MRI supports the understanding and management of these disorders making it an important tool in clinical practice and research.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Cell-cycle-specific regulator of classical non-homologous end joining (NHEJ) of DNA double-strand break (DSB) repair, which can act both as an activator or inhibitor of NHEJ, depending on the cell cycle phase (PubMed : 24610814, PubMed : 28959974). Acts as a regulator of DNA repair pathway choice by specifically inhibiting classical NHEJ during the S and G2 phases, thereby promoting error-free repair by homologous recombination during cell cycle phases when sister chromatids are present (PubMed : 28959974). Preferentially protects single-stranded overhangs at break sites by inhibiting classical NHEJ, thereby creating a local environment that favors homologous recombination (PubMed : 28959974). Acts via interaction with XRCC5/Ku80 and XRCC6/Ku70 (PubMed : 28959974). In contrast, acts as an activator of NHEJ during G1 phase of the cell cycle : promotes classical NHEJ in G1 phase cells via multivalent interactions that increase the affinity of DNA damage response proteins for DSB-associated chromatin. Also involved in immunoglobulin V(D)J recombination (By similarity). May also act as an indirect regulator of proteasome (By similarity).
See full target information CYREN
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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