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AB151118

Anti-MRPS14 antibody

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Rabbit Polyclonal MRPS14 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MRPS14 aa 1 to C-terminus.

대체 명칭 보기

Small ribosomal subunit protein uS14m, MRP-S14, S14mt, MRPS14

3 이미지
Immunocytochemistry/ Immunofluorescence - Anti-MRPS14 antibody (AB151118)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-MRPS14 antibody (AB151118)

Immunofluorescent analysis of PFA/Triton X-100 fixed/permeabilized HEK 293 cells labeling MRPS14 with ab151118 at 4 μg/ml.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS14 antibody (AB151118)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS14 antibody (AB151118)

Immunohistochemical analysis of paraffin-embedded Human stomach tissue labeling MRPS14 with ab151118 at 1/50 dilution.

Western blot - Anti-MRPS14 antibody (AB151118)
  • WB

Unknown

Western blot - Anti-MRPS14 antibody (AB151118)

All lanes:

Western blot - Anti-MRPS14 antibody (ab151118) at 1/250 dilution

Lane 1:

RT 4 cell lysate

Lane 2:

U 251 MG cell lysate

Lane 3:

Human plasma lysate

Lane 4:

Human liver tissue lysate

Lane 5:

Human tonsil cell lysate

Predicted band size: 15 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human MRPS14 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

O60783

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보완 제품

Primary Antibodies

AB79393

Anti-MTCO2 antibody [EPR3314]

20ul selling size|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-MTCO2 antibody [EPR3314] (AB79393)

  • 5
  • 2
Primary Antibodies

AB137120

Anti-IMPDH2 + IMPDH1 antibody [EPR9678(B)]

RabMAb|Recombinant

Western blot - Anti-IMPDH2 + IMPDH1 antibody [EPR9678(B)] (AB137120)

  • 0
  • 0
Primary Antibodies

AB229229

Anti-RFC1 antibody - C-terminal

Immunocytochemistry/ Immunofluorescence - Anti-RFC1 antibody - C-terminal (AB229229)

  • 0
  • 0
Assay Kits

AB212159

Human Parkin ELISA Kit

Recombinant|SimpleStep

ELISA - Human Parkin ELISA Kit (AB212159)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

MRPS14 also known as mitochondrial ribosomal protein S14 is a component of the mitochondrial ribosome small subunit (28S). This protein plays an essential mechanical role in mitochondrial protein synthesis. It has a mass of approximately 16 kDa. MRPS14 is expressed in mitochondria and you find it in cells across a wide range of human tissues. It participates in translation processes specific to the mitochondrial environment showing its critical involvement in cellular energy production.
Biological function summary

Mitochondrial ribosomal protein S14 is vital for the synthesis of proteins that are encoded by mitochondrial DNA. It forms part of the mitochondrial ribosome complex collaborating with other mitochondrial ribosomal proteins to translate mitochondrial mRNA into functional polypeptides. This protein manufacturing process is necessary for the assembly of oxidative phosphorylation complexes which are key components of energy production in cells. The efficient function of MRPS14 is important for maintaining cellular metabolic activity.

Pathways

MRPS14 plays a role in the mitochondrial translation pathway which includes the steps necessary for converting genetic instructions into functional proteins within the mitochondria. It also intersects with the oxidative phosphorylation pathway where it supports energy production by enabling the synthesis of essential respiratory chain proteins. MRPS14 works closely with other mitochondrial ribosomal proteins like MRPS11 and MRPS16 contributing to the assembly and function of the mitochondrial ribosome.

MRPS14 has been linked to mitochondrial dysfunction which is implicated in disorders such as mitochondrial myopathy and MELAS syndrome (Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-like episodes). These conditions typically arise due to disruptions in energy production processes within mitochondria. Interaction with proteins such as MRPL44 and MRPS22 which also play roles in mitochondrial protein synthesis can affect the overall pathological outcomes in mitochondrial diseases.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information MRPS14
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal of experimental & clinical cancer research : CR 43:330 PubMed39721999

2024

OTULIN confers cisplatin resistance in osteosarcoma by mediating GPX4 protein homeostasis to evade the mitochondrial apoptotic pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Zehang Zheng,Yunhao Zeng,Xing Bao,Chuang Huang,Fengjing Guo,Fei Xu,Zhengqiang Luo
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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