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AB187906

Anti-MRPS9 antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal MRPS9 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human MRPS9 aa 1-150.

대체 명칭 보기

RPMS9, MRPS9, Small ribosomal subunit protein uS9m, MRP-S9, S9mt

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS9 antibody (AB187906)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MRPS9 antibody (AB187906)

Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling MRPS9 with ab187906 at 1/200 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-MRPS9 antibody (AB187906)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-MRPS9 antibody (AB187906)

Immunofluorescence analysis of A-431cells labeling MRPS9 with ab187906 at 4μg/ml.

Western blot - Anti-MRPS9 antibody (AB187906)
  • WB

Supplier Data

Western blot - Anti-MRPS9 antibody (AB187906)

All lanes:

Western blot - Anti-MRPS9 antibody (ab187906) at 1/100 dilution

Lane 1:

Human cell line RT-4 lysate

Lane 2:

Human cell line U-251MG sp lysate

Secondary

All lanes:

HRP-conjugated swine anti-rabbit immunoglobulin at 1/3000 dilution

Predicted band size: 46 kDa

true

Exposure time: 1min

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human MRPS9 aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

P82933

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보완 제품

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

MRPS9 also known as mitochondrial ribosomal protein S9 is a protein involved in mitochondrial protein synthesis. Its molecular mass is approximately 43 kDa. It is expressed in the mitochondria across a variety of tissues. This protein assists in assembling the small subunit of the mitochondrial ribosome which aids in the translation of mitochondrial mRNA into functional proteins contributing to cellular energy production.
Biological function summary

MRPS9 functions as part of the mitochondrial ribosome complex specifically the 28S subunit. It plays an essential role in the process of translating mitochondrial-encoded genes which are critical for the oxidative phosphorylation pathway. MRPS9's proper function ensures the synthesis of proteins that are vital for mitochondrial function and energy production in cells.

Pathways

MRPS9 contributes significantly to the mitochondrial translation pathway which is essential for the oxidative phosphorylation system. This system is important for energy production in cells. Within the translation pathway MRPS9 interacts with other ribosomal proteins such as MRPL37 and MRPS18. These interactions facilitate the translation and synthesis of proteins important for maintaining mitochondrial function and energy homeostasis.

MRPS9 is connected to conditions involving mitochondrial dysfunctions such as mitochondrial myopathy. Such disorders often result from impaired energy production due to defective mitochondrial translation. In these conditions there are often interactions noted with proteins like MRPL44 and other components of the oxidative phosphorylation system illustrating the interconnectedness between mitochondrial ribosomal proteins and cellular energy defects.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information MRPS9
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

American journal of human genetics 112:59-74 PubMed39701103

2024

Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype.

Applications

Unspecified application

Species

Unspecified reactive species

Thomas B Smith,Robert Kopajtich,Leigh A M Demain,Alessandro Rea,Huw B Thomas,Manuel Schiff,Christian Beetz,Shelagh Joss,Gerard S Conway,Anju Shukla,Mayuri Yeole,Periyasamy Radhakrishnan,Hatem Azzouz,Amel Ben Chehida,Monique Elmaleh-Bergès,Ruth I C Glasgow,Kyle Thompson,Monika Oláhová,Langping He,Emma M Jenkinson,Amir Jahic,Inna A Belyantseva,Melanie Barzik,Jill E Urquhart,James O'Sullivan,Simon G Williams,Sanjeev S Bhaskar,Samantha Carrera,Alexander J M Blakes,Siddharth Banka,Wyatt W Yue,Jamie M Ellingford,Henry Houlden,Kevin J Munro,Thomas B Friedman,Robert W Taylor,Holger Prokisch,Raymond T O'Keefe,William G Newman

Life science alliance 1:e201800070 PubMed30456350

2018

Proteomics and neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.

Applications

Unspecified application

Species

Unspecified reactive species

Hannelore Hartmann,Daniel Hornburg,Mareike Czuppa,Jakob Bader,Meike Michaelsen,Daniel Farny,Thomas Arzberger,Matthias Mann,Felix Meissner,Dieter Edbauer
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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