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AB188257

Anti-MS4A10 antibody - N-terminal

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Rabbit Polyclonal MS4A10 antibody. N-terminal. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MS4A10 aa 1-100.

대체 명칭 보기

CD20L7, MS4A9, MS4A10, Membrane-spanning 4-domains subfamily A member 10, CD20 antigen-like 7

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS4A10 antibody - N-terminal (AB188257)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MS4A10 antibody - N-terminal (AB188257)

Immunohistochemical analysis of paraffin embedded Human corpus uterine tissue labeling MS4A10 with ab188257 at 1/200 dilution

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human MS4A10 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q96PG2

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보완 제품

Assay Kits

AB113851

DCFDA / H2DCFDA - Cellular ROS Assay Kit

Functional Studies (Act) - DCFDA / H2DCFDA - Cellular ROS Assay Kit (AB113851)

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Assay Kits

AB118970

Lipid Peroxidation (MDA) Assay Kit (Colorimetric/Fluorometric)

Biochemical assay - Lipid Peroxidation (MDA) Assay Kit (Colorimetric/Fluorometric) (AB118970)

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  • 3
Assay Kits

AB113852

TMRE-Mitochondrial Membrane Potential Assay Kit

Functional Studies - TMRE-Mitochondrial Membrane Potential Assay Kit (AB113852)

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Assay Kits

AB65354

Superoxide Dismutase Activity Assay Kit (Colorimetric)

Functional Studies - Superoxide Dismutase Activity Assay Kit (Colorimetric) (AB65354)

  • 4
  • 2
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

MS4A10 also known as Membrane-Spanning 4-Domains Subfamily A Member 10 is a membrane protein with a molecular mass of approximately 25 kDa. It belongs to the MS4A family characterized by four transmembrane domains. MS4A10 is mainly expressed in fetal tissues but shows notable expression in adult tissues like the colon and small intestine. The protein is localized in the cellular membrane implying its potential role in signal transduction processes within these tissues.
Biological function summary

This protein participates in cellular signaling and communication influencing immune responses. While it is not reported as a part of a major protein complex MS4A10 associates closely with other MS4A family members. These interactions suggest involvement in modulating immune cell functions perhaps by mediating cell surface signaling pathways or acting as a receptor or co-receptor on specific immune cells.

Pathways

MS4A10 links to the cell signaling pathways involved in immune response regulation. It shows associations with signaling pathways such as the MAPK pathway and the JAK-STAT pathway. These pathways play significant roles in cell proliferation differentiation and apoptosis. MS4A10 may interact with related proteins such as other MS4A family members within these pathways affecting the signal transduction mechanisms they govern.

Significant alterations or dysregulation of MS4A10 expression have associations with colorectal cancer and inflammatory bowel disease (IBD). In colorectal cancer MS4A10 possibly interacts with other proteins such as MS4A1 suggesting a role in tumorigenesis or cancer cell survival. In IBD alterations in MS4A10 expression might affect immune processes linking it to proteins that modulate inflammation contributing to disease pathology.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May be involved in signal transduction as a component of a multimeric receptor complex.
See full target information MS4A10
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Genes & development 14:2757-70 PubMed11069892

2000

Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.

Applications

Unspecified application

Species

Unspecified reactive species

T Tomonaga,K Nagao,Y Kawasaki,K Furuya,A Murakami,J Morishita,T Yuasa,T Sutani,S E Kearsey,F Uhlmann,K Nasmyth,M Yanagida
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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