Anti-MTAP antibody [MTAP/1813] - BSA and Azide free
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Mouse Monoclonal MTAP antibody. Carrier free. Suitable for IHC-P, WB, Protein Array and reacts with Human, Recombinant full length protein - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MTAP aa 50-200.
대체 명칭 보기
MSAP, MTAP, S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAPase
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MTAP antibody [MTAP/1813] - BSA and Azide free (AB237868)
Formalin-fixed, paraffin-embedded human kidney tissue stained for MTAP using ab237868 at 2 μg/ml in immunohistochemical analysis.
- Protein Array
Unknown
Protein Array - Anti-MTAP antibody [MTAP/1813] - BSA and Azide free (AB237868)
This data was produced with ab238024, the same antibody in a different formulation with BSA and Azide.
ab238024 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
- WB
Supplier Data
Western blot - Anti-MTAP antibody [MTAP/1813] - BSA and Azide free (AB237868)
All lanes:
Western blot - Anti-MTAP antibody [MTAP/1813] (<a href='/ko/products/primary-antibodies/mtap-antibody-mtap-1813-ab238024'>ab238024</a>) at 2 µg/mL
All lanes:
A431 (human epidermoid carcinoma cell line) cell lysate
Predicted band size: 31 kDa
false
Reactivity 정보
특성 및 보관 정보
제형
Purification 테크닉
Purification 관련 사항
보관 버퍼
배송 시 보관 조건
적절한 단기 보관 기간
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Methylthioadenosine phosphorylase plays a significant role in the salvage pathways for methionine and adenine critical for cellular growth and proliferation. MTAP operates as a part of a complex metabolic network involved in polyamine metabolism. In addition to its metabolic functions MTAP contributes to the regulation of the immune response and cell cycle. MTAP immunohistochemistry is often used to study its expression patterns in various tissues.
Pathways
Methylthioadenosine phosphorylase participates importantly in the polyamine biosynthesis and methionine salvage pathways. These pathways are integral for maintaining cellular homeostasis and nucleotide pools. MTAP works closely with proteins such as methionine adenosyltransferase (MAT) and adenosylmethionine decarboxylase (AMD). In concert they facilitate the regeneration of methionine highlighting MTAP's role in cellular adaptation to metabolic demands.
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타겟 정보
제품이 사용된 논문 (1)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Cell 187:3120-3140.e29 PubMed38714197
2024
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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