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AB150381

Anti-MUC4 antibody [EPR9308]

3

(2 리뷰들)

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(5 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal MUC4 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 5 publications.

대체 명칭 보기

Mucin-4, MUC-4, Ascites sialoglycoprotein, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin, ASGP, MUC4

5 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded Human colon tissue labeling MUC4 with unpurified ab150381 at a 1/50 dilution.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon tissue sections labeling MUC4 with purified ab150381 at 1 : 750 dilution (1.44 μg/ml). Heat mediated antigen retrieval was performed using ab93684 (Tris/EDTA buffer, pH 9.0). Tissue was counterstained with hematoxylin. ImmunoHistoProbe one step HRP Polymer (ready to use) secondary antibody was used. PBS instead of the primary antibody was used as the negative control.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded Human Stomach adenocarcinoma tissue using unpurified ab150381 showing -ve staining.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded Human Pancreatic carcinoma tissue using unpurified ab150381 showing +ve staining.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [EPR9308] (AB150381)

Immunohistochemical analysis of paraffin embedded normal Human pancreas tissue using unpurified ab150381 showing -ve staining.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

관련 conjugated 항체와 다양한 조성의 항체 (1)

  • Carrier free

    Anti-MUC4 antibody [EPR9308] - BSA and Azide free

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR9308

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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대체품

Primary Antibodies

AB60720

Anti-MUC4 antibody [5B12]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [5B12] (AB60720)

  • 4
  • 2
Primary Antibodies

AB263957

Anti-MUC4 antibody [3C7.D8.E11.F5]

Western blot - Anti-MUC4 antibody [3C7.D8.E11.F5] (AB263957)

  • 0
  • 0
Primary Antibodies

AB214220

Anti-MUC4 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody (AB214220)

  • 0
  • 0
Primary Antibodies

AB183320

Anti-MUC4 antibody [SP241] - C-terminal

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [SP241] - C-terminal (AB183320)

  • 0
  • 0
Primary Antibodies

AB267547

Alexa Fluor® 647 Anti-MUC4 antibody [SP241]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-MUC4 antibody [SP241] (AB267547)

  • 0
  • 0
Primary Antibodies

AB243921

Anti-MUC4 antibody [SP241] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC4 antibody [SP241] - BSA and Azide free (AB243921)

  • 0
  • 0
Primary Antibodies

AB267546

Alexa Fluor® 488 Anti-MUC4 antibody [SP241]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 488 Anti-MUC4 antibody [SP241] (AB267546)

  • 0
  • 0

보완 제품

Primary Antibodies

AB110641

Anti-BRG1 antibody [EPNCIR111A]

20ul selling size|BOND RX™ Validated|Recombinant|KO Validated|Advanced Validation|RabMAb

ChIC/CUT&RUN sequencing - Anti-BRG1 antibody [EPNCIR111A] (AB110641)

  • 5
  • 10
Primary Antibodies

AB223846

Anti-Gastric Mucin/MUC-6 antibody [EPR20623]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Gastric Mucin/MUC-6 antibody [EPR20623] (AB223846)

  • 4
  • 2
Primary Antibodies

AB109185

Anti-MUC1 antibody [EPR1023]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MUC1 antibody [EPR1023] (AB109185)

  • 0
  • 1
Primary Antibodies

AB16667

Anti-Ki67 antibody [SP6]

BOND RX™ Validated|KO Validated|RabMAb|Advanced Validation|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ki67 antibody [SP6] (AB16667)

  • 5
  • 133
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/750", "IHCP-species-notes": "<p><strong>For unpurified use at 1:50 - 1:100. </strong></p>" } } }
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제품 세부 정보

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
배송 시 보관 조건
Conditional Ambient
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Membrane-bound mucin, a family of highly glycosylated proteins that constitute the major component of the mucus, the slimy and viscous secretion covering epithelial surfaces (PubMed : 10880978). These glycoproteins play important roles in the protection of the epithelium and are implicated in epithelial renewal and differentiation (PubMed : 10880978). Regulates cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and its ability to act as an intramembrane ligand for ERBB2. Plays an important role in proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. In polarized epithelial cells, segregates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor. The interaction with ERBB2 leads to enhanced expression of CDKN1B. The formation of a MUC4-ERBB2-ERBB3-NRG1 complex leads to down-regulation of CDKN1B, resulting in repression of apoptosis and stimulation of proliferation. Its ability to promote tumor growth may be mainly due to repression of apoptosis as opposed to proliferation.
See full target information MUC4
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제품이 사용된 논문 (5)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell reports. Medicine 6:101990 PubMed40054460

2025

Self-assembled patient-derived tumor-like cell clusters for personalized drug testing in diverse sarcomas.

Applications

Unspecified application

Species

Unspecified reactive species

Tian Gao,Xinyu He,Junyi Wang,Jiayong Liu,Xiongbing Hu,Chujie Bai,Shenyi Yin,Yunfei Shi,Yanmin Wang,Zhichao Tan,Fang Cao,Shu Li,Yan-Jie Shi,Ruifeng Xue,Juan Li,Yang He,Jiaxin Li,Huinan Lu,Hanshuo Zhang,Lu Zhang,Zhiwei Fang,Xinyu Wang,Mengmeng Liu,Wenjun Fu,Lei Tang,Buqing Ye,Zhengfu Fan,Jianzhong Jeff Xi

Nature genetics 55:2175-2188 PubMed37985817

2023

Multiomic analysis of cervical squamous cell carcinoma identifies cellular ecosystems with biological and clinical relevance.

Applications

Unspecified application

Species

Unspecified reactive species

Junpeng Fan,Funian Lu,Tianyu Qin,Wenju Peng,Xucui Zhuang,Yinuo Li,Xin Hou,Zixuan Fang,Yunyi Yang,Ensong Guo,Bin Yang,Xi Li,Yu Fu,Xiaoyan Kang,Zimeng Wu,Lili Han,Gordon B Mills,Xiangyi Ma,Kezhen Li,Peng Wu,Ding Ma,Gang Chen,Chaoyang Sun

Journal of nanobiotechnology 21:79 PubMed36882792

2023

Uterine luminal-derived extracellular vesicles: potential nanomaterials to improve embryo implantation.

Applications

Unspecified application

Species

Unspecified reactive species

Linjun Hong,Xupeng Zang,Qun Hu,Yanjuan He,Zhiqian Xu,Yanshe Xie,Ting Gu,Huaqiang Yang,Jie Yang,Junsong Shi,Enqin Zheng,Sixiu Huang,Zheng Xu,Dewu Liu,Gengyuan Cai,Zicong Li,Zhenfang Wu

Heliyon 5:e02753 PubMed31844699

2019

Assessing the prognostic significance of MUC4β in mucoepidermoid carcinoma of the salivary glands: An immunohistochemical study.

Applications

Unspecified application

Species

Unspecified reactive species

Poonam R Sawant,Anita Spadigam,Anita Dhupar,Shaheen Syed,Karla Carvalho

Oncotarget 7:39332-39344 PubMed27322428

2016

Analysis of the correlation between lipotoxicity and pituitary-thyroid axis hormone levels in men and male rats.

Applications

Unspecified application

Species

Unspecified reactive species

Jianmei Yang,Xiaoming Zhou,Xu Zhang,Jianting Hu,Ling Gao,Yongfeng Song,Chunxiao Yu,Shanshan Shao,Zhongshang Yuan,Yan Sun,Huili Yan,Guimei Li,Jiajun Zhao
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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