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AB281513

Anti-Myelin oligodendrocyte glycoprotein antibody [EPR23469-62] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal Myelin oligodendrocyte glycoprotein antibody. Carrier free. Suitable for sELISA and reacts with Mouse, Human samples.

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Myelin-oligodendrocyte glycoprotein, MOG

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Sandwich ELISA - Anti-Myelin oligodendrocyte glycoprotein antibody [EPR23469-62] - BSA and Azide free (Capture) (AB281513)
  • sELISA

Unknown

Sandwich ELISA - Anti-Myelin oligodendrocyte glycoprotein antibody [EPR23469-62] - BSA and Azide free (Capture) (AB281513)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab282304).

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR23469-62

Isotype

IgG

Carrier free

Yes

Reacts with

Human, Mouse

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB278115

Human Myelin oligodendrocyte glycoprotein ELISA Kit (MOG)

Recombinant|SimpleStep

Sandwich ELISA - Human Myelin oligodendrocyte glycoprotein ELISA Kit (MOG) (AB278115)

  • 5
  • 1
Primary Antibodies

AB290691

Anti-MAG/GMA antibody [EPR24276-1] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-MAG/GMA antibody [EPR24276-1] - BSA and Azide free (Detector) (AB290691)

  • 0
  • 0
Primary Antibodies

AB281154

Anti-Chromogranin C/SGII antibody [EPR23876-49] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-Chromogranin C/SGII antibody [EPR23876-49] - BSA and Azide free (Capture) (AB281154)

  • 0
  • 0
Primary Antibodies

AB290662

Anti-Brevican antibody [EPR25743-25] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-Brevican antibody [EPR25743-25] - BSA and Azide free (Capture) (AB290662)

  • 0
  • 0
Primary Antibodies

AB318216

Anti-Munc18-1 antibody [EPR27956-33] - BSA and Azide free (Detector)

Recombinant|RabMAb

Sandwich ELISA - Anti-Munc18-1 antibody [EPR27956-33] - BSA and Azide free (Detector) (AB318216)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" }, "Mouse": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab281513 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human/Mouse Myelin-oligodendrocyte glycoprotein. The recommended pair for sandwich ELISA is:
Capture: ab281513, Human/Mouse Myelin-oligodendrocyte glycoprotein Capture Antibody (unconjugated)
Detector: ab281537, Human/Mouse Myelin-oligodendrocyte glycoprotein Detector Antibody (unconjugated)
The reference range value is 6.25 - 400 pg/mL for human and 7.813 - 500 pg/mL for mouse.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Myelin oligodendrocyte glycoprotein (MOG) also known as MOG protein or MOG glycoprotein is a lesser-known but important component of the central nervous system myelin. The MOG protein has a molecular mass of approximately 26 to 28 kDa. You will find it expressed on the surface of myelin sheaths and oligodendrocytes. This protein plays a role in the myelination process acting as a potential adhesive molecule or signaling molecule contributing to the stability and integrity of the myelin structure. Oligodendrocyte staining techniques can help visualize the distribution and expression patterns of MOG making it important for research purposes.
Biological function summary

MOG influences the immune response and possibly adhesion between myelin membranes. Although it does not form part of a larger well-defined complex it may interact with other myelin-associated proteins to contribute to myelin construction and maintenance. MOG's involvement in these processes supports myelin sheath formation and function aiding electrical conduction in nerve cells. The protein's exposure on the myelin membrane makes it a possible target for immune attacks hinting at its role in autoimmunity.

Pathways

MOG is involved in immune responses and central nervous system pathways. One significant pathway is the autoimmune pathway where MOG can engage with or be targeted by autoimmune antibodies. It interacts with other proteins like myelin basic protein (MBP) in maintaining myelin structures and influencing immunological functions. This interaction implies that disturbances in these pathways might contribute to numerous neurological disorders.

MOG plays a critical role in conditions such as multiple sclerosis and neuromyelitis optica. In multiple sclerosis MOG is a target of autoantibodies leading to demyelination and loss of neural function. In neuromyelitis optica MOG antibodies may contribute to severe inflammation and damage in optic nerves and spinal cord. The connection between MOG and these diseases highlights associations with other proteins like aquaporin-4 which are similarly targeted in associated autoimmune responses. Understanding these relationships is key for developing diagnostics or therapies involving MOG ELISA methods to detect MOG-specific antibodies in patient samples.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.. (Microbial infection) Acts as a receptor for rubella virus.
See full target information MOG
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Product promise

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