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AB238912

Anti-Myoneurin antibody

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Rabbit Polyclonal Myoneurin antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human MYNN aa 50-350.

대체 명칭 보기

OSZF, ZBTB31, SBBIZ1, MYNN, Myoneurin, Zinc finger and BTB domain-containing protein 31

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myoneurin antibody (AB238912)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Myoneurin antibody (AB238912)

Paraffin-embedded human placenta tissue stained for Myoneurin using ab238912 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human MYNN aa 50-350. The exact immunogen used to generate this antibody is proprietary information.

Q9NPC7

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity greater than 95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Myoneurin also known as MYNN is a protein involved in transcription regulation. This protein has a molecular mass of approximately 78 kDa. It shows expression in a variety of tissues but is particularly enriched in the skeletal muscle and central nervous system. Myoneurin's role stems from its capacity to interact with DNA and influence the transcription of specific genes which makes it significant in cellular and developmental processes.
Biological function summary

Myoneurin contributes to regulating gene expression. It acts as a part of multi-protein complexes required in nucleosome remodeling and transcription activation. Through these complexes Myoneurin alters chromatin structure facilitating the accessibility of transcription factors to DNA. This function is important for the fine-tuning of gene expression that affects cell cycle progression and differentiation especially within muscular and neural contexts.

Pathways

Several processes partly depend on Myoneurin. Notably it involves the muscle cell differentiation pathway and neural development. It interacts with proteins such as MEF2 a transcription factor that modulates gene expression in muscle cells and CREB implicated in long-term memory formation both participating in gene regulatory networks coordinated by Myoneurin. These interactions suggest its role in gene pathways that govern tissue-specific functional outcomes.

Myoneurin is linked to certain muscular and neurodegenerative conditions. Alterations or deficiencies in Myoneurin expression relate to muscle atrophy and have been studied in contexts like muscular dystrophies. Additionally Myoneurin's interaction with proteins like SMN linked with spinal muscular atrophy highlights its potential involvement in neuromuscular disorders. Understanding these connections could advance therapeutic strategies for these diseases.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of biological sciences 20:1045-1063 PubMed38322121

2024

The homeoprotein HOXB2 limits triple-negative breast carcinogenesis via extracellular matrix remodeling.

Applications

Unspecified application

Species

Unspecified reactive species

Ji Hoon Oh,Clara Yuri Kim,Da Som Jeong,Yu Cheon Kim,Myoung Hee Kim,Je-Yoel Cho
제품이 사용된 논문 모두 보기

Product promise

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