Mouse Monoclonal NAPSIN A antibody. Suitable for IHC-P, WB, Protein Array and reacts with Human, Recombinant full length protein - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human NAPSA aa 150-300.
대체 명칭 보기
NAP1, NAPA, NAPSA, Napsin-A, Aspartyl protease 4, Napsin-1, TA01/TA02, ASP4, Asp 4
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NAPSIN A antibody [NAPSA/1238] (AB234002)
Formalin-fixed, paraffin-embedded human lung adenocarcinoma tissue stained for NAPSIN A using ab234002 at 2 μg/ml in immunohistochemical analysis.
- Protein Array
Unknown
Protein Array - Anti-NAPSIN A antibody [NAPSA/1238] (AB234002)
ab234002 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
- WB
Supplier Data
Western blot - Anti-NAPSIN A antibody [NAPSA/1238] (AB234002)
All lanes:
Western blot - Anti-NAPSIN A antibody [NAPSA/1238] (ab234002) at 2 µg/mL
Lane 1:
K562 (human chronic myelogenous leukemia cell line from bone marrow) cell lysate
Lane 2:
HEK-293 (human epithelial cell line from embryonic kidney) cell lysate
Lane 3:
A549 (human chronic lung carcinoma cell line) cell lysate
Predicted band size: 45 kDa
false
Reactivity 정보
특성 및 보관 정보
제형
Purification 테크닉
Purification 관련 사항
보관 버퍼
배송 시 보관 조건
적절한 단기 보관 기간
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Napsin A functions in the maturation of pulmonary surfactant proteins which are essential for normal lung function. Napsin A cleaves surfactant protein B an important component of the surfactant system in alveolar air spaces allowing proper lung mechanics. While napsin A operates in concert with other enzymes it does not form part of a larger complex. Its role impacts cellular processes related to respiratory physiology and contributes to the regulation of protein breakdown within the cell.
Pathways
Napsin A is involved in respiratory and proteolytic pathways influencing lung physiology and systemic protein metabolism. One important pathway is the surfactant metabolism pathway which ensures adequate surfactant levels for maintaining lung function. Napsin A is related to surfactant proteins like surfactant protein B through this pathway facilitating their activation and processing.
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제품이 사용된 논문 (1)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Bioactive materials 50:364-381 PubMed40589547
2025
Applications
Unspecified application
Species
Unspecified reactive species
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