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AB221456

Anti-Netrin G1 antibody

1

(1 리뷰)

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(2 제품이 사용된 논문 )

Rabbit Polyclonal Netrin G1 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human NTNG1 aa 1-100.

대체 명칭 보기

KIAA0976, LMNT1, UNQ571/PRO1133, NTNG1, Netrin-G1, Laminet-1

1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-Netrin G1 antibody (AB221456)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Netrin G1 antibody (AB221456)

Immunofluorescent analysis of paraformaldehyde-fixed, Triton X-100 permeabilized BJ cells labeling Netrin G1 with ab221456 at 4 μg/mL dilution (green).

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human NTNG1 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q9Y2I2

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보완 제품

Primary Antibodies

AB122903

Anti-Netrin 1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Netrin 1 antibody (AB122903)

  • 0
  • 0
Primary Antibodies

AB216463

Anti-VGLUT2 antibody [EPR21085]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-VGLUT2 antibody [EPR21085] (AB216463)

  • 4
  • 1
Primary Antibodies

AB185200

Anti-Netrin-3 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Netrin-3 antibody (AB185200)

  • 0
  • 0
Primary Antibodies

AB273570

Anti-DCC antibody [EPR23313-115]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DCC antibody [EPR23313-115] (AB273570)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Netrin G1 also known as Netrin-G1 or NTNG1 is a protein involved in axonal guidance. This protein helps in the development and differentiation of the central nervous system. It has a mass of approximately 64 kDa. Netrin G1 is expressed in brain regions such as the hippocampus and cerebral cortex. Unlike other netrins it is tethered to the membrane through a glycosylphosphatidylinositol (GPI) anchor affecting its signaling properties.
Biological function summary

Netrin G1 plays a significant role in neuronal circuit formation. It interacts with ligands like NGL1 and NGL2 to mediate cell signaling pathways that guide axonal growth and synapse formation. While it is not a part of a molecular complex on its own its association with these partners enhances its functionality in synaptic connectivity and neural network maintenance.

Pathways

Netrin G1 engages in the axon guidance pathway and is involved in nervous system development processes. It works alongside proteins such as Netrin-1 to influence the direction and growth of axons. Through these interactions Netrin G1 contributes to the precise wiring of the nervous system required for proper function. Understanding its role in these pathways provides insight into the molecular mechanisms of neural development.

Changes in Netrin G1 expression and function have been linked to neuropsychiatric conditions like schizophrenia and autism spectrum disorders. Studies suggest that Netrin G1 through its interaction with other proteins like Netrin-1 and DCC can alter synaptic connectivity which may play a role in the pathology of these conditions. These associations make Netrin G1 a potential target for therapeutic interventions in related neurological disorders.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites.
See full target information NTNG1
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature neuroscience 28:1146-1159 PubMed40442499

2025

The transcriptomes, connections and development of submucosal neuron classes in the mouse small intestine.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Li,Khomgrit Morarach,Ziwei Liu,Sanghita Banerjee,Yanan Chen,Ashley L Harb,Joel M Kosareff,Charles R Hall,Fernando López-Redondo,Elham Jalalvand,Suad H Mohamed,Anastassia Mikhailova,David R Linden,Ulrika Marklund

Protein & cell 12:557-577 PubMed32683582

2020

Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.

Applications

Unspecified application

Species

Unspecified reactive species

Yu-Kun Xia,Yi-Rong Zeng,Meng-Li Zhang,Peng Liu,Fang Liu,Hao Zhang,Chen-Xi He,Yi-Ping Sun,Jin-Ye Zhang,Cheng Zhang,Lei Song,Chen Ding,Yu-Jie Tang,Zhen Yang,Chen Yang,Pu Wang,Kun-Liang Guan,Yue Xiong,Dan Ye
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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